ABCC6

Gene Symbol	ABCC6
Entrez Gene	368
Alt Symbol	ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7
Species	Human
Gene Type	protein-coding
Description	ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Other Description	ATP-binding cassette sub-family C member 6|anthracycline resistance-associated protein|multi-specific organic anion transporter E|multidrug resistance-associated protein 6
Swissprots	A8Y988 A2RRN8 P78420 A8KIG6 E7ESW8 Q8TCY8 O95255 Q9UMZ7
Accessions	AAC15785 EAW53950 EAW53951 EAW53952 O95255 AF076622 AAC79696 AF168791 AAD51293 AI074459 AK298295 BAG60553 AM711638 CAN84639 AM774324 CAO81806 AY078405 AAL83711 BC050733 AAH50733 BC131732 AAI31733 DC361874 XM_011522479 XP_011520781 XM_011522480 XP_011520782 XM_011522481 XP_011520783 XM_011522482 XP_011520784 XM_011546696 XP_011544998 XM_011546697 XP_011544999 XR_932836 XR_932837 XR_932838 XR_951901 XR_951902 XR_951903 NM_001079528 NP_001072996 NM_001171 NP_001162
Function	Isoform 1: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS). {ECO:0000269|PubMed:11880368}.
Subcellular Location	Isoform 1: Basolateral cell membrane {ECO:0000269|PubMed:12901863, ECO:0000269|PubMed:23625951}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12901863, ECO:0000269|PubMed:23625951}.
Tissue Specificity	Expressed in kidney and liver. Very low expression in other tissues.
Top Pathways	ABC transporters

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MRP6 full length protein - ab131889 from Abcam Category Protein Source Wheat germ Species Human

Human MRP6 protein fragment - ab114729 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human MRP6 Protein - H00000368-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MRP6 Partial Recombinant Protein - H00000368-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ABCC6-Antibody-C-term-Blocking-peptide - BP10101b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ABCC6 / MRP6 - H00000368-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ABCC6 / MRP6 - H00000368-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ABCC6 / MRP6 - H00000368-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ABCC6 / MRP6 - H00000368-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ABCC6 fusion protein - Ag18640 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

ABCC6 fusion protein - ag18540 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ABCC, His-tagged - ABCC6-9219H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human ABCC6 - ABCC6-632H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Hu01 from Cloud-clone Category Protein Source E.coli Species Human

ABCC6 Peptide - abx164638 from Abbexa Category Peptide Species Human

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

ABCC6 Peptide, Human - M34GP00057H from Creative Peptides Category Peptide Source Synthetic. Species Human

MRP6 Recombinant Protein Antigen - NBP2-55262PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Multidrug resistance-associated protein 6 (ABCC6), partial, Recombinant Protein - MBS1035685 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human ABCC6 Protein, GST-Tagged - ABCC6-051H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human ABCC6 Protein, GST-Tagged - ABCC6-052H from Creative Biomart Category Protein Source Wheat Germ Species Human

Search more