CCNH

Gene Symbol CCNH
Entrez Gene 902
Alt Symbol CAK, CycH, p34, p37
Species Human
Gene Type protein-coding
Description cyclin H
Other Description CAK complex subunit|CDK-activating kinase complex subunit|MO15-associated protein|cyclin-H|cyclin-dependent kinase-activating kinase complex subunit
Swissprots Q8TBL9 P51946 Q53X72
Accessions AAL74271 EAW95934 EAW95935 P51946 AB209342 BAD92579 AI761780 AK094534 AK291720 BAF84409 BC005280 AAH05280 BC016705 AAH16705 BC016823 AAH16823 BC022351 AAH22351 BF510957 BG718714 BP244381 BX537673 CB240639 CR407658 CAG28586 DA079651 DQ892550 ABM83476 DQ895761 ABM86687 U11791 AAA21361 U12685 AAA57006 XM_005248627 XP_005248684 XM_005248629 XP_005248686 XM_011543706 XP_011542008 NM_001199189 NP_001186118 NM_001239 NP_001230
Function Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. {ECO:0000269|PubMed:10024882, ECO:0000269|PubMed:7533895}.
Subcellular Location Nucleus.
Top Pathways Cell cycle, Nucleotide excision repair, Basal transcription factors

Cyclin H Antibody - 2927 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Jurkat and Raji cells, using Cyclin H Antibody.

cyclin H (D-10) - sc-1662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cyclin H (D-10): sc-1662. Western blot analysis of cyclin H expression in Jurkat (A), A-431 (B), K-562 (C), C32 (D), MM-142 (E) and NIH/3T3 (F) nuclear extracts.

cyclin H (C-18) - sc-609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cyclin H (C-18): sc-609. Western blot analysis of cyclin H expression in cell extracts (UPPER PANEL) and purified polyhistidine tagged cyclin H fusion protein (LOWER PANEL). Cells tested include Jurkat (A), A-431 (B) and K-562 (C). Antibody concentrations tested for analysis of recombinant cyclin H protein include 0.1 µg/ml (D), 0.05 µg/ml (E), 0.01 µg/ml (F) and 0.001 µg/ml (G).

cyclin H (FL-323) - sc-855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of cyclin H expression in Jurkat (A), A-431 (B), K-562 (C), C32 (D,E) and NIH/3T3 (F) whole cell lysates. Antibodies tested include cyclin H (C-18): sc-609 (A-D) and cyclin H (FL-323): sc-855 (E,F).

Anti-Cyclin H (phospho T315) antibody - ab73208 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cyclin H (phospho T315) antibody (ab73208) at 1/500 dilutionLane 1 : HeLa cell extractLane 2 : HeLa cell extract with immunising phosphopeptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Cyclin H antibody - ab54903 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Cyclin H antibody (ab54903) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human testis.

Anti-Cyclin H antibody - ab170216 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow Cytometric analysis of HeLa cells with ab170216 antibody at a dilution of 1/10 (right histogram) compared to a negative control cell (left histogram).

Anti-Cyclin H antibody - ab89257 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Cyclin H antibody (ab89257) at 5 µg/ml + human kidney lysate at 50 µgSecondaryHRP goat anti mouse IgG at 1/2500 dilution

Anti-Cyclin H antibody - ab136027 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cyclin H antibody (ab136027) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-Cyclin H antibody - ab10542 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Cyclin H antibody [1B8] - ab124409 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1B8
Anti-Cyclin H antibody [1B8] (ab124409) at 1/500 dilution + HeLa cell lysate

Anti-Cyclin H antibody [2125C2a] - ab71966 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2125C2a
Anti-Cyclin H antibody [2125C2a] (ab71966) + immunising recombinant protein

Anti-Cyclin H antibody [4E11-G2-D7] - ab131187 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E11-G2-D7
All lanes : Anti-Cyclin H antibody [4E11-G2-D7] (ab131187) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : K562 cell lysateLane 3 : A431 cell lysate

Anti-Cyclin H antibody [EPR3928] - ab111933 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3928
All lanes : Anti-Cyclin H antibody [EPR3928] (ab111933) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : A431 cell lsyateLane 3 : K562 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.

Anti-Cyclin H antibody [EPR3929] - ab92376 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3929
All lanes : Anti-Cyclin H antibody [EPR3929] (ab92376)Lane 1 : Jurkat cell lysateLane 2 : A431 cell lysateLane 3 : K562 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CCNH / Cyclin H Antibody - LS-C331195 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cell using CCNH antibody. Blue: DAPI for nuclear staining.

Anti-CCNH / Cyclin H Antibody (clone 1B8) IHC-plus™ - LS-B6020 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1B8
Anti-CCNH / Cyclin H antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6020 concentration 5 ug/ml.

Anti-CCNH / Cyclin H Antibody - LS-C22576 from LifeSpan Bioscience

Prices $475.00
Sizes 150 µg
Host Mouse
Clonality Monoclonal

Anti-CCNH / Cyclin H Antibody - LS-C64121 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-CCNH / Cyclin H Antibody (clone 2125C2a) - LS-C184681 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2125C2a

Anti-CCNH / Cyclin H Antibody (aa267-299, AP) - LS-C208261 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNH / Cyclin H Antibody (C-Terminus) - LS-C102865 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CCNH / Cyclin H antibody LS-C102865 Western blot of MCF7 cell lysate.

Anti-CCNH / Cyclin H Antibody - LS-C178271 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot detection of CCNH in Jurkat,K562&A431 cell lysates using CCNH antibody (1:1000 diluted).

Anti-CCNH / Cyclin H Antibody (aa274-323) - LS-C117869 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells, using Cyclin H (Ab-315) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CCNH / Cyclin H Antibody (aa267-299, APC) - LS-C208262 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more