CCNH

Gene Symbol CCNH
Entrez Gene 902
Alt Symbol CAK, CycH, p34, p37
Species Human
Gene Type protein-coding
Description cyclin H
Other Description CAK complex subunit|CDK-activating kinase complex subunit|MO15-associated protein|cyclin-H|cyclin-dependent kinase-activating kinase complex subunit
Swissprots Q8TBL9 P51946 Q53X72
Accessions AAL74271 EAW95934 EAW95935 P51946 AB209342 BAD92579 AI761780 AK094534 AK291720 BAF84409 BC005280 AAH05280 BC016705 AAH16705 BC016823 AAH16823 BC022351 AAH22351 BF510957 BG718714 BP244381 BX537673 CB240639 CR407658 CAG28586 DA079651 DQ892550 ABM83476 DQ895761 ABM86687 U11791 AAA21361 U12685 AAA57006 XM_005248627 XP_005248684 XM_005248629 XP_005248686 XM_011543706 XP_011542008 NM_001199189 NP_001186118 NM_001239 NP_001230
Function Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. {ECO:0000269|PubMed:10024882, ECO:0000269|PubMed:7533895}.
Subcellular Location Nucleus.
Top Pathways Cell cycle, Nucleotide excision repair, Basal transcription factors

cyclin H CRISPR/Cas9 KO Plasmid (h) - sc-416523 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H HDR Plasmid (h) - sc-416523-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H Double Nickase Plasmid (h) - sc-416523-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H Double Nickase Plasmid (h2) - sc-416523-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H CRISPR Activation Plasmid (h) - sc-416523-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H CRISPR Activation Plasmid (h2) - sc-416523-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H Lentiviral Activation Particles (h) - sc-416523-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H Lentiviral Activation Particles (h2) - sc-416523-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin H siRNA (h) - sc-29290 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cyclin H shRNA Plasmid (h) - sc-29290-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cyclin H shRNA (h) Lentiviral Particles - sc-29290-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cyclin H RNAi - H00000902-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU003751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5640 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00839 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00839

CCNH siRNA (Human) - CRH0634 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCNH - MBS8212830 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CCNH (NM_001239.3) - SHH257941 from Creative biogene

Category siRNA
Species Reactivities Human

Human CCNH siRNA - orb261136 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCNH shRNA Plasmid (Human) - CHH0634 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCNH miRNA 3'UTR clone - MiUTR3H-04526 from Creative biogene

Species Reactivities Human
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