CLTC

Gene Symbol CLTC
Entrez Gene 1213
Alt Symbol CHC, CHC17, CLH-17, CLTCL2, Hc
Species Human
Gene Type protein-coding
Description clathrin, heavy chain (Hc)
Other Description clathrin heavy chain 1|clathrin heavy chain on chromosome 17|clathrin, heavy polypeptide (Hc)|clathrin, heavy polypeptide-like 2
Swissprots Q86TF2 Q6N0A0 D3DU00 Q00610
Accessions EAW94395 EAW94396 EAW94397 EAW94398 EAW94399 Q00610 AB073891 AK127134 BC015854 BC036430 AAH36430 BC051800 AAH51800 BC054489 AAH54489 BX473803 BX640615 CAE45761 D21260 BAA04801 DA248028 X55878 CAA39363 XM_005257012 XP_005257069 XM_011524279 XP_011522581 XM_011524280 XP_011522582 XM_011524281 XP_011522583 NM_001288653 NP_001275582 NM_004859 NP_004850
Function Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
Subcellular Location Cytoplasmic vesicle membrane {ECO:0000269|PubMed:17081065}; Peripheral membrane protein {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Membrane, coated pit {ECO:0000269|PubMed:17081065}; Peripheral membrane protein {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways Huntington's disease, Endocytosis, Lysosome, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption

Clathrin Heavy Chain (D3C6) XP ® Rabbit mAb - 4796 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3C6
Western blot analysis of extracts from various cell lines using Clathrin Heavy Chain (D3C6) XP ® Rabbit mAb.

Clathrin Heavy Chain (P1663) Antibody - 2410 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from SHSY5Y, Neuro2A, PC12 and COS cells, using Clathrin Heavy Chain (P1663) Antibody.

Clathrin Heavy Chain (I67) Antibody - 2419 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from SHSY5Y, Neuro2A, C6, COS cells and rat brain lysate, using Clathrin Heavy Chain (I67) Antibody.

Clathrin HC (A-8) - sc-271178 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Clathrin HC (A-8): sc-271178. Western blot analysis of Clathrin HC expression in HeLa (A) and NIH/3T3 (B) whole cell lysates.

Clathrin HC (B-5) - sc-271252 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Clathrin HC (B-5): sc-271252. Western blot analysis of Clathrin HC expression in NIH/3T3 (A) and HeLa (B) whole cell lysate.

Clathrin HC (STo 3H9) - sc-53225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Clathrin HC (STo 3H9): sc-53225. Western blot analysis of Clathrin HC expression in Raji whole cell lysate.

Clathrin HC (C-20) - sc-6579 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Clathrin HC (C-20): sc-6579. Rhodamine immunofluores-cence staining of methanol-fixed A-431 cells showing localized staining within the cytoplasm.

Clathrin HC (H-300) - sc-9069 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Clathrin HC (H-300): sc-9069. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Clathrin HC (N-19) - sc-6580 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Clathrin HC (N-19): sc-6580. Western blot analysis of Clathrin HC expression in HeLa whole cell lysate.

Clathrin HC (E-11) - sc-271253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Clathrin HC (E-11): sc-271253. Western blot analysis of Clathrin HC expression in NIH/3T3 (A) and HeLa (B) whole cell lysate.

Clathrin HC (3F132) - sc-58714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Clathrin HC (3F132): sc-58714. Western blot analysis of Clathrin HC expression in HeLa (A), NIH/3T3 (B), KNRK (C), A-431 (D), HL-60 (E) and Raji (F) whole cell lysates.

Anti-Clathrin heavy chain antibody - ab21679 from Abcam

Prices $404.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab21679 stained human HeLa cells. The cells were methanol fixed (5 min) and incubated with the antibody (ab21679, 1µg/ml) for 1h at room temperature. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Image-iTTM FX Signal Enhancer was used as the primary blocking agent, 5% BSA (in TBS-T) was used for all other blocking steps. DAPI was used to stain the cell nuclei (blue). Alexa Fluor® 594 WGA was used to label plasma membranes (red).

Anti-Clathrin heavy chain antibody [3F132] - ab14406 from Abcam

Prices $370.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone 3F132

Anti-Clathrin heavy chain antibody [STo 3H9] - ab10822 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone STo 3H9

Anti-CLTC / Clathrin Heavy Chain Antibody (Internal) IHC-plus™ - LS-B4174 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CLTC antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4174 concentration 3.75 ug/ml.

Anti-CLTC / Clathrin Heavy Chain Antibody (aa619-638) - LS-C79380 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (aa207-264) - LS-C79382 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (N-Terminus) - LS-C79383 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (aa150-413) - LS-C128187 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (clone STo 3H9) - LS-C142779 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (clone BF-06) - LS-C112396 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone BF-06

Anti-CLTC / Clathrin Heavy Chain Antibody (aa1024-1054, AP) - LS-C255089 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (aa1024-1054, Biotin) - LS-C255091 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (aa1024-1054, APC) - LS-C255090 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLTC / Clathrin Heavy Chain Antibody (aa1024-1054, PE) - LS-C255096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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