CLTC

Gene Symbol CLTC
Entrez Gene 1213
Alt Symbol CHC, CHC17, CLH-17, CLTCL2, Hc
Species Human
Gene Type protein-coding
Description clathrin, heavy chain (Hc)
Other Description clathrin heavy chain 1|clathrin heavy chain on chromosome 17|clathrin, heavy polypeptide (Hc)|clathrin, heavy polypeptide-like 2
Swissprots Q86TF2 Q6N0A0 D3DU00 Q00610
Accessions EAW94395 EAW94396 EAW94397 EAW94398 EAW94399 Q00610 AB073891 AK127134 BC015854 BC036430 AAH36430 BC051800 AAH51800 BC054489 AAH54489 BX473803 BX640615 CAE45761 D21260 BAA04801 DA248028 X55878 CAA39363 XM_005257012 XP_005257069 XM_011524279 XP_011522581 XM_011524280 XP_011522582 XM_011524281 XP_011522583 NM_001288653 NP_001275582 NM_004859 NP_004850
Function Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
Subcellular Location Cytoplasmic vesicle membrane {ECO:0000269|PubMed:17081065}; Peripheral membrane protein {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Membrane, coated pit {ECO:0000269|PubMed:17081065}; Peripheral membrane protein {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways Huntington's disease, Endocytosis, Lysosome, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption

Clathrin HC CRISPR/Cas9 KO Plasmid (h) - sc-400863 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC HDR Plasmid (h) - sc-400863-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC Double Nickase Plasmid (h) - sc-400863-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC Double Nickase Plasmid (h2) - sc-400863-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC CRISPR Activation Plasmid (h) - sc-400863-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC CRISPR Activation Plasmid (h2) - sc-400863-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC Lentiviral Activation Particles (h) - sc-400863-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC Lentiviral Activation Particles (h2) - sc-400863-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC siRNA (h) - sc-35067 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Clathrin HC shRNA Plasmid (h) - sc-35067-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Clathrin HC shRNA (h) Lentiviral Particles - sc-35067-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Clathrin Heavy Chain 1/CHC17 RNAi - H00001213-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU039481 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6271 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6271 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLTC siRNA (Human) - CRH0865 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLTC - MBS8236766 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Clathrin HC CRISPR/Cas9 KO Plasmid (h2) - sc-400863-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Clathrin HC HDR Plasmid (h2) - sc-400863-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human CLTC (NM_004859.3) - SHH265757 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CLTC(NM_004859.3) - SHG184855 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLTC siRNA - orb261367 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLTC shRNA Plasmid (Human) - CHH0865 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLTC miRNA 3'UTR clone - MiUTR1H-02242 from Creative biogene

Species Reactivities Human
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