| Gene Symbol |
Il1rl1
|
| Entrez Gene |
17082
|
| Alt Symbol |
DER4, Fit-1, Ly84, ST2L, St2, St2-rs1, T1, T1/ST2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
interleukin 1 receptor-like 1
|
| Other Description |
interleukin-1 receptor-like 1|lymphocyte antigen 84
|
| Swissprots |
Q05208 P14719
|
| Accessions |
CAA42742 EDL14575 EDL14576 P14719 AI573400 AK033417 BAC28277 AK145118 BAE26245 AK167968 AK167971 BC033416 BC051445 AAH51445 BY228016 D13695 BAA02854 M24843 AAA40160 Y07519 CAA68812 XM_006495741 XP_006495804 XM_006495743 XP_006495806 XM_006495744 XP_006495807 NM_001025602 NP_001020773 NM_001294171 NP_001281100 NM_010743 NP_034873
|
| Function |
Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 (By similarity). Possibly involved in helper T-cell function. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Predominantly expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines. {ECO:0000269|PubMed:8131748}.
|