Gene Symbol | Il1rl1 |
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Entrez Gene | 17082 |
Alt Symbol | DER4, Fit-1, Ly84, ST2L, St2, St2-rs1, T1, T1/ST2 |
Species | Mouse |
Gene Type | protein-coding |
Description | interleukin 1 receptor-like 1 |
Other Description | interleukin-1 receptor-like 1|lymphocyte antigen 84 |
Swissprots | Q05208 P14719 |
Accessions | CAA42742 EDL14575 EDL14576 P14719 AI573400 AK033417 BAC28277 AK145118 BAE26245 AK167968 AK167971 BC033416 BC051445 AAH51445 BY228016 D13695 BAA02854 M24843 AAA40160 Y07519 CAA68812 XM_006495741 XP_006495804 XM_006495743 XP_006495806 XM_006495744 XP_006495807 NM_001025602 NP_001020773 NM_001294171 NP_001281100 NM_010743 NP_034873 |
Function | Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 (By similarity). Possibly involved in helper T-cell function. {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Predominantly expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines. {ECO:0000269|PubMed:8131748}. |
ST2 CRISPR/Cas9 KO Plasmid (m) - sc-421502 from Santa Cruz Biotechnology
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ST2 HDR Plasmid (m) - sc-421502-HDR from Santa Cruz Biotechnology
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ST2 Double Nickase Plasmid (m) - sc-421502-NIC from Santa Cruz Biotechnology
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ST2 Double Nickase Plasmid (m2) - sc-421502-NIC-2 from Santa Cruz Biotechnology
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ST2 CRISPR Activation Plasmid (m) - sc-421502-ACT from Santa Cruz Biotechnology
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ST2 CRISPR Activation Plasmid (m2) - sc-421502-ACT-2 from Santa Cruz Biotechnology
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ST2 Lentiviral Activation Particles (m) - sc-421502-LAC from Santa Cruz Biotechnology
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ST2 Lentiviral Activation Particles (m2) - sc-421502-LAC-2 from Santa Cruz Biotechnology
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ST2 siRNA (m) - sc-40036 from Santa Cruz Biotechnology
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ST2 shRNA Plasmid (m) - sc-40036-SH from Santa Cruz Biotechnology
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ST2 shRNA (m) Lentiviral Particles - sc-40036-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU047141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33770 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33770 from Sigma-Aldrich
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IL1RL1 siRNA (Mouse) - CRM2413 from Cohesion Biosciences
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IL1RL1 - MBS8215577 from MyBioSource
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shRNA set against Mouse Il1rl1 (NM_010743.2) - SHH318609 from Creative biogene
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Mouse ST2 siRNA - orb281889 from Biorbyt
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IL1RL1 shRNA Plasmid (Mouse) - CHM2413 from Cohesion Biosciences
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