MAPK13

Gene Symbol	MAPK13
Entrez Gene	5603
Alt Symbol	MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase 13
Other Description	MAP kinase 13|MAP kinase p38 delta|mitogen-activated protein kinase p38 delta|stress-activated protein kinase 4
Swissprots	Q5U4A5 Q9UNU0 Q6FI46 O15264 O15124 O14739
Accessions	EAX03874 EAX03875 EAX03876 O15264 AB209586 BAD92823 AB451221 BAG70035 AB451344 BAG70158 AF004709 AAC51374 AF015256 AAC51758 AF092535 AAD23377 AF100546 AAF36772 AK222922 BAD96642 AK308018 BC000433 AAH00433 BC001641 AAH01641 BC004428 AAH04428 BC085196 AAH85196 BM921729 BT007221 AAP35885 CR536490 CAG38729 CR541687 CAG46488 DB335275 DB473379 DQ588728 DQ891372 ABM82298 DQ894551 ABM85477 DR006449 EU832156 ACE87506 EU832250 ACE86820 U93232 AAB87639 Y10488 CAA71512 NM_002754 NP_002745 NR_072996
Function	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-regulation of the gene expression of CXCL14. Plays an importan
Tissue Specificity	Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells. {ECO:0000269|PubMed:10201954, ECO:0000269|PubMed:9374491}.
Top Pathways	VEGF signaling pathway, Inflammatory mediator regulation of TRP channels, Sphingolipid signaling pathway, Retrograde endocannabinoid signaling, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAPK13 / p38delta ELISA Kit (Sandwich ELISA) - LS-F9247 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.156-10 ng/ml

Human Phospho-p38 delta (T180/Y182) DuoSet IC ELISA, 2 Plate - DYC2124-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 156.00 - 10,000 pg/mL

Human MAPK13 ELISA Kit - abx152269 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mitogen Activated Protein Kinase 14 (MAPK14), Human, ELISA Kit - SEB206Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.56ng/mL Range 1.56-100ng/mL

MAPK13 (Human) IP-WB Antibody Pair - H00005603-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

MAPK13 (Human) IP-WB Antibody Pair - H00005603-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

MAPK13 (Human) IP-WB Antibody Pair - H00005603-PW3 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

MAPK13 (Human) Matched Antibody Pair - H00005603-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Mitogen Activated Protein Kinase 13 (MAPK13), ELISA Kit - MBS2021670 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.061ng/mL. Range 0.156-10ng/mL

ELISA Kit for Mitogen Activated Protein Kinase 13 (MAPK13) - SED578Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Mitogen Activated Protein Kinase 13 (MAPK13) - SED578Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mitogen Activated Protein Kinase 13 (MAPK13), Human, ELISA Kit - DL-MAPK13-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

MAPK P38 (P38 Mitogen-activated Protein Kinase), CLIA Kit - MBS2532675 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 4.688ng/mL Range 7.813~500ng/mL

Human MAPK13 ELISA Kit - abx571724 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human MAPK13 ELISA Kit - E024701 from Biobool Category ELISA Kit Sensitivity Typically less than 0.061ng/mL.

MAPK13 ELISA Kit (Human) (OKCD00395) - OKCD00395 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.061 ng/mL Range 0.156-10 ng/mL

MAPK13 ELISA Kit (Human) (OKDD00386) - OKDD00386 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.061 ng/mL Range 0.156-10 ng/mL

Human Mitogen-activated protein kinase 13 (MAPK13) ELISA Kit - AE34317HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.061 ng/mL Range 0.156-10 ng/mL

Mitogen Activated Protein Kinase 13 (MAPK13), ELISA Kit - MBS454842 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.061ng/mL Range 0.156-10ng/mL

P38 Mitogen-activated Protein Kinase, ELISA Kit - MBS764658 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.75ng/ml Range 1.25-80ng/ml

Mitogen Activated Protein Kinase 13 (MAPK13), ELISA Kit - MBS9374480 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

P38 Mitogen-Activated Protein Kinase, ELISA Kit - MBS765087 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.75ng/ml Range 1.25-80ng/ml

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