Car2

Gene Symbol Car2
Entrez Gene 12349
Alt Symbol AI131712, CAII, Ca2, Car-2, Ltw-5, Lvtw-5
Species Mouse
Gene Type protein-coding
Description carbonic anhydrase 2
Other Description CA II|CA-II|carbonate dehydratase II|carbonic anhydrase II
Swissprots Q9DCY9 Q7TPE1 Q9DCT3 P00920 Q6LDQ7
Accessions AAA37357 EDL05130 P00920 AK002333 BAB22019 AK002498 BAB22146 AK146015 BC044806 BC055291 AAH55291 BU946040 CD774528 K00811 AAA37356 M25944 AAA39505 U37705 U37706 XM_006530050 XP_006530113 NM_009801 NP_033931
Function Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000269|PubMed:20150244}.
Subcellular Location Cytoplasm. Cell membrane {ECO:0000250}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells (By similarity). {ECO:0000250}.
Top Pathways Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion

CA II CRISPR/Cas9 KO Plasmid (m) - sc-419452 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II HDR Plasmid (m) - sc-419452-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II Double Nickase Plasmid (m) - sc-419452-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II Double Nickase Plasmid (m2) - sc-419452-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II CRISPR Activation Plasmid (m) - sc-419452-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II CRISPR Activation Plasmid (m2) - sc-419452-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II Lentiviral Activation Particles (m) - sc-419452-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II Lentiviral Activation Particles (m2) - sc-419452-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CA II siRNA (m) - sc-29866 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CA II shRNA Plasmid (m) - sc-29866-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CA II shRNA (m) Lentiviral Particles - sc-29866-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN27982 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27982 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CA2 siRNA (Mouse) - CRM0495 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CA2 - MBS827046 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Car2 (NM_009801.4) - SHH254597 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Car2(NM_009801.4) - SHG140965 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse CA2 siRNA - orb279971 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CA2 shRNA Plasmid (Mouse) - CHM0495 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

CAR2 miRNA 3'UTR clone - MiUTR1M-02516 from Creative biogene

Species Reactivities Mouse
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