LIPA

Gene Symbol LIPA
Entrez Gene 3988
Alt Symbol CESD, LAL
Species Human
Gene Type protein-coding
Description lipase A, lysosomal acid, cholesterol esterase
Other Description acid cholesteryl ester hydrolase|cholesterol ester hydrolase|cholesteryl esterase|lysosomal acid lipase|lysosomal acid lipase/cholesteryl ester hydrolase|sterol esterase
Swissprots Q5T074 B2RBH5 Q96EJ0 Q53H21 D3DR29 Q16529 Q5T771 P38571
Accessions AAB60327 EAW50140 EAW50141 EAW50142 P38571 AK091558 BAG52380 AK096406 BAG53281 AK125193 BAC86078 AK130882 AK222760 BAD96480 AK290241 BAF82930 AK293491 BAG56978 AK297079 BAG59596 AK314665 BAG37222 AU135835 BC012287 AAH12287 CA435432 DA275550 DA394611 DA466221 HQ447241 ADQ31728 HY150944 M74775 AAA59519 S68069 AAB29185 U08464 AAB60328 X76488 CAA54026 Z31690 CAA83495 NM_000235 NP_000226 NM_001127605 NP_001121077 NM_001288979 NP_001275908 NR_110233
Function Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Subcellular Location Lysosome.
Top Pathways Lysosome, Steroid biosynthesis

LAL (9G7F12) - sc-58374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LAL (9G7F12): sc-58374. Western blot analysis of LAL expression in human brain (A), human lung (B) and human spleen (C) tissue extracts and HeLa (D) whole cell lysate.

LAL (W-20) - sc-54028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Lysosomal acid lipase antibody - ab73445 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Lysosomal acid lipase antibody (ab73445) at 1 µg/mlLane 1 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 2 : HT 1080 (Human fibrosarcoma) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Lysosomal acid lipase antibody - ab154356 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Lysosomal acid lipase antibody (ab154356) at 1/1000 dilution + Mouse liver whole cell lysate at 50 µg

Anti-Lysosomal acid lipase antibody - ab89771 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Lysosomal acid lipase antibody (ab89771) at 1 µg/ml + human pancreas tissue lysate at 50 µg

Anti-Lysosomal acid lipase antibody [9G7F12] - ab36597 from Abcam

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9G7F12
All lanes : Anti-Lysosomal acid lipase antibody [9G7F12] (ab36597)Lane 1 : Molecular weight markerLane 2 : Truncated LAL recombinant protein

Anti-LIPA / Lysosomal Acid Lipase Antibody (aa1-399) - LS-C130568 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (clone GF1) - LS-C190301 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-LIPA / Lysosomal Acid Lipase Antibody - LS-C310880 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody - LS-C285553 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (HRP) - LS-C317412 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (FITC) - LS-C317411 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (Biotin) - LS-C317782 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (FITC) - LS-C317783 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (HRP) - LS-C317784 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (aa42-91) - LS-C135924 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LIPA antibody LS-C135924 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-LIPA / Lysosomal Acid Lipase Antibody (aa32-358) - LS-C314951 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LIPA / Lysosomal Acid Lipase.

Anti-LIPA / Lysosomal Acid Lipase Antibody - LS-C317785 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (Biotin) - LS-C318892 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIPA / Lysosomal Acid Lipase Antibody (aa32-201) - LS-C314950 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LIPA / Lysosomal Acid Lipase.

Anti-LIPA / Lysosomal Acid Lipase Antibody (clone 1F9) - LS-C197618 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F9
Western Blot analysis of LIPA expression in transfected 293T cell line by LIPA monoclonal antibody (M01), clone 1F9.Lane 1: LIPA transfected lysate(45 KDa).Lane 2: Non-transfected lysate.

Anti-LIPA / Lysosomal Acid Lipase Antibody (aa150-300) IHC-plus™ - LS-B7733 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Lysosomal Acid Lipase / LAL antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7733 dilution 1:100.

Lipase A Antibody - NBP1-54155 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Lipase A Antibody [NBP1-54155] - WB detection of LIPA in HepG2 whole cell extract.

Lipase A Antibody - NBP2-19360 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Lipase A Antibody [NBP2-19360] - Sample (50 ug of whole cell lysate) A: Mouse Liver, 10% SDS PAGE gel, diluted at 1:1000.

Lipase A Antibody (1F9) - H00003988-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F9
Western Blot: Lipase A Antibody (1F9) [H00003988-M01] - Analysis of LIPA expression in transfected 293T cell line by LIPA monoclonal antibody (M01), clone 1F9.Lane 1: LIPA transfected lysate(45 KDa).Lane 2: Non-transfected lysate.
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