LIPA

Gene Symbol	LIPA
Entrez Gene	3988
Alt Symbol	CESD, LAL
Species	Human
Gene Type	protein-coding
Description	lipase A, lysosomal acid, cholesterol esterase
Other Description	acid cholesteryl ester hydrolase|cholesterol ester hydrolase|cholesteryl esterase|lysosomal acid lipase|lysosomal acid lipase/cholesteryl ester hydrolase|sterol esterase
Swissprots	Q5T074 B2RBH5 Q96EJ0 Q53H21 D3DR29 Q16529 Q5T771 P38571
Accessions	AAB60327 EAW50140 EAW50141 EAW50142 P38571 AK091558 BAG52380 AK096406 BAG53281 AK125193 BAC86078 AK130882 AK222760 BAD96480 AK290241 BAF82930 AK293491 BAG56978 AK297079 BAG59596 AK314665 BAG37222 AU135835 BC012287 AAH12287 CA435432 DA275550 DA394611 DA466221 HQ447241 ADQ31728 HY150944 M74775 AAA59519 S68069 AAB29185 U08464 AAB60328 X76488 CAA54026 Z31690 CAA83495 NM_000235 NP_000226 NM_001127605 NP_001121077 NM_001288979 NP_001275908 NR_110233
Function	Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Subcellular Location	Lysosome.
Top Pathways	Lysosome, Steroid biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Lysosomal acid lipase full length protein - ab152501 from Abcam Category Protein Source Wheat germ Species Human

Lysosomal acid lipase peptide - ab87127 from Abcam Category Peptide

Recombinant human Lysosomal acid lipase/cholesteryl ester hydrolase (OPCA00151) - OPCA00151 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human LIPA protein - orb244349 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

LIPA - H00003988-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

LIPA fusion protein - ag3627 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human LIPA, MYC/DDK-tagged - LIPA-11H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Lipase A, Lysosomal Acid (LIPA) - RPD225Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Lipase A, Lysosomal Acid (LIPA) - RPD225Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Lipase A, Lysosomal Acid (LIPA) - RPD225Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase - CSB-EP012972HU CSB-BP012972HU CSB-MP012972HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase - CSB-EP012972HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase(LIPA) - CSB-YP012972HU CSB-BP012972HU CSB-MP012972HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Lysosomal acid lipase/cholesteryl ester hydrolase - RPC140834 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

LIPA Protein - abx163745 from Abbexa Category Protein Species Human

LIPA (transcript variant 2) - TP301637 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase - AP70507 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Lysosomal acid lipase/cholesteryl ester hydrolase, Recombinant Protein - MBS9420421 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Lysosomal acid lipase/cholesteryl ester hydrolase, Recombinant Protein - MBS965818 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell

LIPA Recombinant Protein (Human) (OPCA05069) - OPCA05069 from Aviva Systems Biology Category Protein Species Human

Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) - RPC21612 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

Recombinant Human Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) - RPC24795 from Biomatik Category Protein Prices $224.00, $410.00, $2,030.00 Sizes 50 µg, 100 µg, 1 mg Source Yeast Species Human

Human LIPA protein - orb54581 from Biorbyt Category Protein Species Human

Recombinant Human LIPA Protein (22-399 aa), His-tagged - LIPA-2158H from Creative Biomart Category Protein Source Yeast Species Human

Recombinant Human LIPA Protein (22-399 aa), GST-tagged - LIPA-627H from Creative Biomart Category Protein Source E. coli Species Human

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