TP53BP1

Gene Symbol	TP53BP1
Entrez Gene	7158
Alt Symbol	53BP1, p202, p53BP1
Species	Human
Gene Type	protein-coding
Description	tumor protein p53 binding protein 1
Other Description	p53-binding protein 1|tumor protein 53-binding protein, 1|tumor protein p53-binding protein, 1|tumor suppressor p53-binding protein 1
Swissprots	Q2M1Z7 Q7Z3U4 Q12888 Q5FWZ3 Q4LE46 F8VY86
Accessions	AAW69392 EAW92604 EAW92605 Q12888 AB210025 BAE06107 AF078776 AAC62018 AK123418 BAG53901 AK125173 AK292915 BAF85604 AK295764 BAH12183 AK307405 BC017846 AAH17846 BC063119 BC112161 AAI12162 BP228994 BX537418 CAD97660 U09477 AAA21596 XM_005254635 XP_005254692 XM_011521984 XP_011520286 XM_011521985 XP_011520287 XM_011521986 XP_011520288 XR_931898 XR_931899 NM_001141979 NP_001135451 NM_001141980 NP_001135452 NM_005657 NP_005648
Function	Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation. {ECO:0000269|PubMed:12364621, ECO:0000269|PubMed:17190600, ECO:0000269|PubMed:21144835}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. H4K20me2 is required for efficient localization to double strand breaks and removal of proteins that have a high affinity for H4K20me2 such as L3MBTL1 and KDM4A is needed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human 53BP1 peptide - ab98293 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Recombinant Human 53BP1 Protein - H00007158-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TP53BP1 - H00007158-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TP53BP1 - H00007158-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human TP53BP1, His-tagged - TP53BP1-26025TH from Creative Biomart Category Protein Source E. coli

Recombinant Human TP53BP1, GST-tagged - TP53BP1-15H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Tumor Protein p53 Binding Protein 1 (TP53BP1) - RPH009Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

53BP1 Blocking Peptide - CBP3348 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

53BP1 (D2) Peptide - AP0418P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

53BP1 (D2) Peptide - BS1714P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Tumor Protein p53 Binding Protein 1 (TP53BP1) - RPH009Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Tumor suppressor p53-binding protein 1(TP53BP1) ,partial - CSB-YP613268HU CSB-EP613268HU CSB-BP613268HU CSB-MP613268HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TP53BP1 (transcript variant 3) - TP318016 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

53BP1 Blocking Peptide - abx162210 from Abbexa Category Peptide Species Human, Mouse, Rat

TP53BP1 Peptide, Human - M34GP16454H from Creative Peptides Category Peptide Source Synthetic. Species Human

TP53BP1 Recombinant Protein (OPCD07653) - OPCD07653 from Aviva Systems Biology Category Protein Source E.coli Species Human

53BP1 Recombinant Protein Antigen - NBP2-54677PEP from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µl Source E.coli Species Human

53BP1 Recombinant Protein Antigen - NBP2-54659PEP from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µl Source E.coli Species Human

53BP1 Peptide - orb224234 from Biorbyt Category Peptide Species Human, Mouse, Rat

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