| Gene Symbol |
GTF2F1
|
| Entrez Gene |
2962
|
| Alt Symbol |
BTF4, RAP74, TF2F1, TFIIF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
general transcription factor IIF, polypeptide 1, 74kDa
|
| Other Description |
TFIIF-alpha|general transcription factor IIF 74 kDa subunit|general transcription factor IIF subunit 1|transcription initiation factor IIF subunit alpha|transcription initiation factor RAP74
|
| Swissprots |
B2RCS0 Q9BWN0 P35269
|
| Accessions |
EAW69098 EAW69099 P35269 AA323384 AK293124 BAG56676 AK302178 BAG63544 AK315240 BAG37667 BC000120 AAH00120 BC013007 AAH13007 BT007097 AAP35761 CR456798 CAG33079 DQ890597 ABM92214 DQ893766 ABM84692 X64002 CAA45404 X64037 CAA45408 NM_002096 NP_002087
|
| Function |
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. {ECO:0000269|PubMed:10428810}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Basal transcription factors
|
![Western Blot: RAP30 Overexpression Lysate (Adult Normal) [NBL1-11386] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAP30.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1609_RAP30%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11386-img0002.jpg)