| Gene Symbol | NR1H4 |
|---|---|
| Entrez Gene | 540528 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | nuclear receptor subfamily 1, group H, member 4 |
| Other Description | bile acid receptor|farnesoid X-activated receptor|farnesol receptor HRR-1|nuclear receptor subfamily 1 group H member 4 |
| Swissprots | Q3SZL0 |
| Accessions | DAA29555 Q3SZL0 BC102805 AAI02806 XM_005206661 XP_005206718 XM_005206662 XP_005206719 XM_005206663 XP_005206720 NM_001034708 NP_001029880 |
| Function | Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Top Pathways | Bile secretion |
Bile acid receptor (NR1H4), Bovine, ELISA Kit - E11B0957 from ARP American Research Products
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Bile acid receptor, NR1H4, Bovine, ELISA Kit - E2042b from ARP American Research Products
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Nuclear receptor subfamily 1, group H, member 4 (NR1H4), Bovine, ELISA Kit - E11N0563 from ARP American Research Products
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nuclear receptor subfamily 1, group H, member 4 (NR1H4), ELISA Kit - MBS7246881 from MyBioSource
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Bovine NR1H4 ELISA Kit - E091634 from Biobool
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Bile acid receptor, ELISA Kit - MBS2881209 from MyBioSource
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