Got1

Gene Symbol	Got1
Entrez Gene	24401
Alt Symbol	Aspat, Gaspat, cAspAT, cCAT
Species	Rat
Gene Type	protein-coding
Description	glutamic-oxaloacetic transaminase 1, soluble
Other Description	aspartate aminotransferase 1|aspartate aminotransferase, cytoplasmic|cysteine aminotransferase, cytoplasmic|cysteine transaminase, cytoplasmic|cytosolic aspartate aminotransferase|glutamate oxaloacetate transaminase 1, soluble|transaminase A
Swissprots	Q64570 P13221 Q6P721
Accessions	AAA40842 CBF96063 CBF96226 CBV09583 CBV09746 EDL94253 EDL94254 P13221 BC061877 AAH61877 CB578328 CK600227 D00252 BAA00183 FM055803 FN802619 FQ219727 J04171 AAA40769 NM_012571 NP_036703
Function	Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. {ECO:0000269|PubMed:17545671, ECO:0000269|PubMed:21266983, ECO:0000269|PubMed:21361730, ECO:0000269|PubMed:3053674, ECO:0000269|PubMed:3182750, ECO:0000269|PubMed:7113743}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Expressed in liver and kidney. {ECO:0000269|PubMed:3182856}.
Top Pathways	Cysteine and methionine metabolism, Alanine, aspartate and glutamate metabolism, Phenylalanine metabolism, Biosynthesis of amino acids, Tyrosine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Aspartate Aminotransferase (AST), Rat, ELISA Kit - CSB-E13023r from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.78 mIU/ml Range 3.12 mIU/ml-200 mIU/ml

Aspartate Aminotransferase (AST), Rat, ELISA Kit - SEB214Ra from ARP American Research Products Category ELISA Kit Prices $742.00 Sizes 96 t Sensitivity 0.117ng/mL Range 0.312-20ng/mL

Aspartate aminotransferase, cytoplasmic, Got1, Rat, ELISA Kit - E1214r from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 3.12-200 U/L

Rat Aspartate Aminotransferase (AST) ELISA kit - CSB-E13023r from Cusabio Category ELISA Kit Sensitivity 0.78 mIU/ml Range 3.12 mIU/ml-200 mIU/ml

ELISA Kit for Aspartate Aminotransferase (AST) - SEB214Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.34ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Rat AST(Aspartate Aminotransferase) ELISA Kit - E-EL-R0076 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mL Range 0.31~20 ng/mL

Rat Aspartate aminotransferase, cytoplasmic ELISA Kit - abx256448 from Abbexa Category ELISA Kit Range 3.12 U/L - 200 U/L

Rat Aspartate aminotransferase, cytoplasmic ELISA Kit - EKE52240 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 3.12-200 U/L

Got1 - EKR0940 from Nordic BioSite Sensitivity 1.875mIU/ml Range 3.12-200mIU/ml

Got1 - EKR940 from Nordic BioSite Sensitivity 1.875mIU/ml Range 3.12-200mIU/ml

Rat Got1 ELISA Kit - E074203 from Biobool Category ELISA Kit

GOT1 ELISA Kit (Rat) (OKCA00950) - OKCA00950 from Aviva Systems Biology Category ELISA Kit Prices $655.00 Sizes 96 wells Sensitivity 0.78 mIU/mL Range 3.12 mIU/mL-200 mIU/mL

GOT1 ELISA Kit (Rat) (OKEH03319) - OKEH03319 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity < 1.5 U/L Range 3.12 - 200 U/L

Rat Aspartate aminotransferase, cytoplasmic ELISA Kit - EK2977 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 3.12-200 U/L

Aspartate aminotransferase, ELISA Kit - MBS2883911 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <1.5 U/L Range 3.12 U/L -200 U/L

Aspartate aminotransferase, ELISA Kit - MBS9426813 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Range 3.12-200 U/L

Aspartate Aminotransferase (AST) , ELISA Kit - MBS2087796 from MyBioSource Category ELISA Kit Prices $535.00, $820.00, $1,130.00, $4,710.00, $8,490.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.34ng/mL Range 0.781-50ng/mL

Aspartate Aminotransferase (AST), ELISA Kit - MBS451210 from MyBioSource Category ELISA Kit Prices $425.00, $565.00, $2,485.00, $4,830.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.117ng/mL Range 0.312-20ng/mL

Aspartate aminotransferase, cytoplasmic, ELISA Kit - MBS765218 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875mIU/ml Range 3.12-200mIU/ml

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