Gene Symbol |
Flot1
|
Entrez Gene |
14251
|
Alt Symbol |
reggie-2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
flotillin 1
|
Other Description |
flotillin-1
|
Swissprots |
O08917
|
Accessions |
AAO39406 EDL23235 O08917 AF145044 AAD33945 AK150692 BAE29771 AK150827 BAE29889 AK167323 BAE39425 AK178956 AK181092 AK188620 AK190295 AK200487 AK202818 AK210442 AK215579 AK216334 AK216913 AK219942 AY167925 AAN86639 BC004647 AAH04647 U90435 AAB58583 XM_006523656 XP_006523719 XM_006523657 XP_006523720 XM_006536516 XP_006536579 XM_006536517 XP_006536580 XM_006537249 XP_006537312 XM_006537250 XP_006537313 NM_008027 NP_032053
|
Function |
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
|
Subcellular Location |
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Melanosome {ECO:0000250}. Endosome {ECO:0000250}. Note=Membrane-associated protein of caveolae.
|
Tissue Specificity |
High expression in brain, white adipose tissue, heart muscle, skeletal muscle and lung. Low expression in spleen, liver and testis.
|
Top Pathways |
Insulin signaling pathway
|