Gene Symbol | Flot1 |
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Entrez Gene | 14251 |
Alt Symbol | reggie-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | flotillin 1 |
Other Description | flotillin-1 |
Swissprots | O08917 |
Accessions | AAO39406 EDL23235 O08917 AF145044 AAD33945 AK150692 BAE29771 AK150827 BAE29889 AK167323 BAE39425 AK178956 AK181092 AK188620 AK190295 AK200487 AK202818 AK210442 AK215579 AK216334 AK216913 AK219942 AY167925 AAN86639 BC004647 AAH04647 U90435 AAB58583 XM_006523656 XP_006523719 XM_006523657 XP_006523720 XM_006536516 XP_006536579 XM_006536517 XP_006536580 XM_006537249 XP_006537312 XM_006537250 XP_006537313 NM_008027 NP_032053 |
Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. |
Subcellular Location | Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Melanosome {ECO:0000250}. Endosome {ECO:0000250}. Note=Membrane-associated protein of caveolae. |
Tissue Specificity | High expression in brain, white adipose tissue, heart muscle, skeletal muscle and lung. Low expression in spleen, liver and testis. |
Top Pathways | Insulin signaling pathway |
Flotillin-1 CRISPR/Cas9 KO Plasmid (m) - sc-420381 from Santa Cruz Biotechnology
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Flotillin-1 HDR Plasmid (m) - sc-420381-HDR from Santa Cruz Biotechnology
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Flotillin-1 Double Nickase Plasmid (m) - sc-420381-NIC from Santa Cruz Biotechnology
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Flotillin-1 Double Nickase Plasmid (m2) - sc-420381-NIC-2 from Santa Cruz Biotechnology
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Flotillin-1 CRISPR Activation Plasmid (m) - sc-420381-ACT from Santa Cruz Biotechnology
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Flotillin-1 CRISPR Activation Plasmid (m2) - sc-420381-ACT-2 from Santa Cruz Biotechnology
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Flotillin-1 Lentiviral Activation Particles (m) - sc-420381-LAC from Santa Cruz Biotechnology
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Flotillin-1 Lentiviral Activation Particles (m2) - sc-420381-LAC-2 from Santa Cruz Biotechnology
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Flotillin-1 siRNA (m) - sc-35392 from Santa Cruz Biotechnology
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Flotillin-1 shRNA Plasmid (m) - sc-35392-SH from Santa Cruz Biotechnology
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Flotillin-1 shRNA (m) Lentiviral Particles - sc-35392-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU002671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN31435 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31435 from Sigma-Aldrich
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FLOT1 siRNA (Mouse) - CRM1392 from Cohesion Biosciences
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FLOT1 - MBS8221497 from MyBioSource
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shRNA set against Mouse FLOT1 (NM_008027.2) - SHH295701 from Creative biogene
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shRNA set against Mouse Flot1(NM_008027.2) - SHH063173 from Creative biogene
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Mouse FLOT1 siRNA - orb280868 from Biorbyt
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FLOT1 shRNA Plasmid (Mouse) - CHM1392 from Cohesion Biosciences
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FLOT1 miRNA 3'UTR clone - MiUTR1M-04736 from Creative biogene
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