| Gene Symbol |
Irf5
|
| Entrez Gene |
27056
|
| Alt Symbol |
AW491843, mirf5
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
interferon regulatory factor 5
|
| Other Description |
IRF-5|interferon regulatory factor 5 bone marrow
|
| Swissprots |
P56477
|
| Accessions |
EDL13770 P56477 AF028725 AAB81997 AF177019 AK150598 AK151019 BAE30037 AK152042 AK156220 BAE33631 AK171356 AW491843 BC160276 AAI60276 BY749561 BY749804 EU401974 ACA81530 XM_006505095 XP_006505158 XM_006505097 XP_006505160 XM_006505098 XP_006505161 XM_006505099 XP_006505162 XM_006505100 XP_006505163 XM_011241064 XP_011239366 NM_001252382 NP_001239311 NM_012057 NP_036187
|
| Function |
Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18824541}. Nucleus {ECO:0000269|PubMed:18824541}. Note=Shuttles between the nucleus and the cytoplasm.
|
| Top Pathways |
Toll-like receptor signaling pathway
|