Gene Symbol | Irf5 |
---|---|
Entrez Gene | 27056 |
Alt Symbol | AW491843, mirf5 |
Species | Mouse |
Gene Type | protein-coding |
Description | interferon regulatory factor 5 |
Other Description | IRF-5|interferon regulatory factor 5 bone marrow |
Swissprots | P56477 |
Accessions | EDL13770 P56477 AF028725 AAB81997 AF177019 AK150598 AK151019 BAE30037 AK152042 AK156220 BAE33631 AK171356 AW491843 BC160276 AAI60276 BY749561 BY749804 EU401974 ACA81530 XM_006505095 XP_006505158 XM_006505097 XP_006505160 XM_006505098 XP_006505161 XM_006505099 XP_006505162 XM_006505100 XP_006505163 XM_011241064 XP_011239366 NM_001252382 NP_001239311 NM_012057 NP_036187 |
Function | Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18824541}. Nucleus {ECO:0000269|PubMed:18824541}. Note=Shuttles between the nucleus and the cytoplasm. |
Top Pathways | Toll-like receptor signaling pathway |
IRF-5 CRISPR/Cas9 KO Plasmid (m) - sc-424184 from Santa Cruz Biotechnology
|
||||||||
IRF-5 HDR Plasmid (m) - sc-424184-HDR from Santa Cruz Biotechnology
|
||||||||
IRF-5 Double Nickase Plasmid (m) - sc-424184-NIC from Santa Cruz Biotechnology
|
||||||||
IRF-5 Double Nickase Plasmid (m2) - sc-424184-NIC-2 from Santa Cruz Biotechnology
|
||||||||
IRF-5 CRISPR Activation Plasmid (m) - sc-424184-ACT from Santa Cruz Biotechnology
|
||||||||
IRF-5 CRISPR Activation Plasmid (m2) - sc-424184-ACT-2 from Santa Cruz Biotechnology
|
||||||||
IRF-5 Lentiviral Activation Particles (m) - sc-424184-LAC from Santa Cruz Biotechnology
|
||||||||
IRF-5 Lentiviral Activation Particles (m2) - sc-424184-LAC-2 from Santa Cruz Biotechnology
|
||||||||
IRF-5 siRNA (m) - sc-72045 from Santa Cruz Biotechnology
|
||||||||
IRF-5 shRNA Plasmid (m) - sc-72045-SH from Santa Cruz Biotechnology
|
||||||||
IRF-5 shRNA (m) Lentiviral Particles - sc-72045-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU041411 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN33938 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33938 from Sigma-Aldrich
|
||||||||
IRF5 siRNA (Mouse) - CRM4853 from Cohesion Biosciences
|
||||||||
IRF5 - MBS8206866 from MyBioSource
|
||||||||
IRF-5 CRISPR/Cas9 KO Plasmid (m2) - sc-424184-KO-2 from Santa Cruz Biotechnology
|
||||||||
IRF-5 HDR Plasmid (m2) - sc-424184-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Mouse IRF5 siRNA - orb284329 from Biorbyt
|
||||||||
IRF5 shRNA Plasmid (Mouse) - CHM4853 from Cohesion Biosciences
|