CNTN1

Gene Symbol	CNTN1
Entrez Gene	1272
Alt Symbol	F3, GP135, MYPCN
Species	Human
Gene Type	protein-coding
Description	contactin 1
Other Description	contactin-1|glycoprotein gP135|neural cell surface protein F3
Swissprots	Q7M4P0 A8K0Y3 Q8N466 Q14030 Q12860 Q12861 A8K0H9
Accessions	EAW57822 EAW57823 EAW57824 Q12860 AI473107 AK289544 BAF82233 AK289698 BAF82387 BC036569 AAH36569 BM717031 BX648591 BY799936 DA215712 DQ442053 DQ442054 U07819 AAA67920 U07820 AAA67921 Z21488 CAA79696 XM_005268651 XP_005268708 XM_006719241 XP_006719304 XM_011537926 XP_011536228 XM_011537927 XP_011536229 NM_001256063 NP_001242992 NM_001256064 NP_001242993 NM_001843 NP_001834 NM_175038 NP_778203
Function	Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Tissue Specificity	Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. {ECO:0000269|PubMed:2026173, ECO:0000269|PubMed:8164510}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human F3 gene - orb93572 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

CNTN1 - MBS1269150 from MyBioSource Species Human Accession BC036569

Human CNTN1 ORF Clone(NM_001256063.1) - CDCL159305 from Creative Biomart Species Human Accession NM_001256063.1

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10383-M from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10383-ACG from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10383-NH from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10383-CH from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10383-UT from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10383-NF from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10383-NM from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10383-CY from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10383-CF from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10383-NY from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10383-CM from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10383-M-F from Sino Biological Species Human

Human Contactin 1/CNTN1 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10383-ACR from Sino Biological Species Human

Human CNTN1 ORF Clone (BC036569) - CDCS410020 from Creative biogene Species Human Accession Q12860

Human Contactin-1 (CAA79696) VersaClone cDNA - RDC1829 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Human CNTN1 gene - orb90969 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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