NR3C2

Gene Symbol	NR3C2
Entrez Gene	4306
Alt Symbol	MCR, MLR, MR, NR3C2VIT
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 3, group C, member 2
Other Description	aldosterone receptor|mineralocorticoid receptor|mineralocorticoid receptor 1|mineralocorticoid receptor delta
Swissprots	B0ZBF5 B0ZBF7 Q96KQ9 P08235 Q2NKL1 Q96KQ8
Accessions	AAY41033 ACA05923 ACA05924 ACA05926 ACS13715 ACS13716 ACS13718 EAX05008 P08235 AB209056 BAD92293 AJ315514 CAC67405 AJ315515 CAC67406 AK123047 AK304318 BAG65170 BC111758 AAI11759 BQ184536 DB061545 DB232659 M16801 AAA59571 XM_011531975 XP_011530277 XM_011531976 XP_011530278 XM_011531977 XP_011530279 XM_011531978 XP_011530280 NM_000901 NP_000892 NM_001166104 NP_001159576
Function	Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels. {ECO:0000269|PubMed:3037703}.
Subcellular Location	Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane.
Tissue Specificity	Ubiquitous. Highly expressed in distal tubules, convoluted tubules and cortical collecting duct in kidney, and in sweat glands. Detected at lower levels in cardiomyocytes, in epidermis and in colon enterocytes. {ECO:0000269|PubMed:11518808, ECO:0000269|PubMed:9141514}.
Top Pathways	Aldosterone-regulated sodium reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat Mineralocorticoid Receptor ELISA Kit (Sandwich ELISA) - LS-F7441 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.064 ng/ml Range 0.156-10 ng/ml

Human Mineralocorticoid Receptor ELISA Kit (Sandwich ELISA) - LS-F8193 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Human MR ELISA Kit - abx152377 from Abbexa Category ELISA Kit Sensitivity 0.112 ng/ml Range 0.313 ng/ml - 20 ng/ml

Mineralocorticoid Receptor (MR), Human, ELISA Kit - SEA464Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.112ng/mL Range 0.312-20ng/mL

Mineralocorticoid receptor (NR3C2), Human, ELISA Kit - CSB-EL016061HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.56 pg/ml Range 6.25 pg/ml-400 pg/ml

Mineralocorticoid receptor (NR3C2), Human, ELISA Kit - E01M0426 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Mineralocorticoid receptor, NR3C2, Human, ELISA Kit - E0158h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

MR (Mannose Receptor), Human, ELISA Kit - E-EL-H1307 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t Sensitivity 0.094 ng/mL Range 0.156-10ng/mL

Mannose Receptor, MR, Rabbit, ELISA Kit - E-EL-RB1999 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mannose Receptor, MR, Chicken, ELISA Kit - E-EL-Ch2249 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mannose Receptor, MR, Porcine, ELISA Kit - E-EL-P1147 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mannose Receptor, MR, Sheep, ELISA Kit - E-EL-S0272 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Mannose Receptor, MR, Guinea Pig, ELISA Kit - E-EL-GP1207 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mannose Receptor, MR, Monkey, ELISA Kit - E-EL-MK1330 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

nuclear receptor subfamily 3, group C, member 2, ELISA Kit - MBS921692 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.56 pg/ml Range 6.25 pg/ml-400 pg/ml

Human MR (Mannose Receptor) CLIA Kit - E-CL-H0854 from Elabscience Category CLIA Kit Sensitivity 0.094ng/mL Range 0.156~10ng/mL

milk specific allergen antibody (IgE) , ELISA Kit - MBS705693 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mineralocorticoid Receptor, ELISA Kit - MBS092936 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mineralocorticoid Receptor, ELISA Kit - MBS065852 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mineralocorticoid Receptor, ELISA Kit - MBS088385 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mineralocorticoid Receptor, ELISA Kit - MBS079005 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mineralocorticoid Receptor (MR), ELISA Kit - MBS9308819 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mineralocorticoid Receptor (MR), ELISA Kit - MBS2024090 from MyBioSource Category ELISA Kit Prices $345.00, $515.00, $695.00, $2,840.00, $5,180.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.058ng/mL. Range 0.156-10ng/mL

Mineralocorticoid receptor (NR3C2), ELISA Kit - MBS7203360 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Mineralocorticoid Receptor (MR) - SEA464Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.058ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

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