| Gene Symbol |
Cdh17
|
| Entrez Gene |
12557
|
| Alt Symbol |
HPT-1, HPT-1/LI
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cadherin 17
|
| Other Description |
BILL-cadherin|LI-cadherin|P130|cadherin-17|liver-intestine cadherin
|
| Swissprots |
Q9R100
|
| Accessions |
EDL05637 EDL05638 Q9R100 AF177669 AAD51125 AK089791 AK155633 BAE33356 AK171733 BAE42638 BC042891 AAH42891 CF383265 D87912 BAB03264 XM_006537583 XP_006537646 XM_006537584 XP_006537647 NM_019753 NP_062727
|
| Function |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highest expression is found in intestine with lower expression in spleen, bone marrow, lung and testis. No expression detected in liver, kidney, heart, brain or skeletal muscle. Expressed in precursor B-cells and myeloid cells. {ECO:0000269|PubMed:10906147}.
|