| Gene Symbol | Cdh17 |
|---|---|
| Entrez Gene | 12557 |
| Alt Symbol | HPT-1, HPT-1/LI |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | cadherin 17 |
| Other Description | BILL-cadherin|LI-cadherin|P130|cadherin-17|liver-intestine cadherin |
| Swissprots | Q9R100 |
| Accessions | EDL05637 EDL05638 Q9R100 AF177669 AAD51125 AK089791 AK155633 BAE33356 AK171733 BAE42638 BC042891 AAH42891 CF383265 D87912 BAB03264 XM_006537583 XP_006537646 XM_006537584 XP_006537647 NM_019753 NP_062727 |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. |
| Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue Specificity | Highest expression is found in intestine with lower expression in spleen, bone marrow, lung and testis. No expression detected in liver, kidney, heart, brain or skeletal muscle. Expressed in precursor B-cells and myeloid cells. {ECO:0000269|PubMed:10906147}. |