CRYAA

Gene Symbol CRYAA
Entrez Gene 1409
Alt Symbol CRYA1, CTRCT9, HSPB4
Species Human
Gene Type protein-coding
Description crystallin, alpha A
Other Description alpha-crystallin A chain|crystallin, alpha-1|heat shock protein beta-4|human alphaA-crystallin (CRYA1)
Swissprots Q53X53 P02489
Accessions AAA52105 AAA52106 AAB21309 AAB33370 AAB99912 BAA95535 EAX09497 EAX09498 P02489 BC069528 AAH69528 BC113598 AAI13599 BE552434 BM679139 BX118596 CR407691 CAG28619 HQ258067 ADR82821 HQ448434 ADQ32914 L25781 AAC37570 U05569 AAA97523 U66584 AAC50900 X14789 CAA32891 XM_005261093 XP_005261150 NM_000394 NP_000385
Function Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. {ECO:0000269|PubMed:22120592}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue Specificity Expressed in eye lens. {ECO:0000269|PubMed:12356833}.
Top Pathways Protein processing in endoplasmic reticulum

αA-crystallin CRISPR/Cas9 KO Plasmid (h) - sc-402047 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin HDR Plasmid (h) - sc-402047-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin Double Nickase Plasmid (h) - sc-402047-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin Double Nickase Plasmid (h2) - sc-402047-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin CRISPR Activation Plasmid (h) - sc-402047-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin CRISPR Activation Plasmid (h2) - sc-402047-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin Lentiviral Activation Particles (h) - sc-402047-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin Lentiviral Activation Particles (h2) - sc-402047-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αA-crystallin siRNA (h) - sc-40430 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

αA-crystallin shRNA Plasmid (h) - sc-40430-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

αA-crystallin shRNA (h) Lentiviral Particles - sc-40430-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU003721 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6603 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04587 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04587

CRYAA siRNA (Human) - CRH0991 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRYAA - MBS8240563 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRYAA (NM_000394.2) - SHH269897 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CRYAA(NM_000394.2) - SHG200941 from Creative biogene

Category siRNA
Species Reactivities Human

CRYAA shRNA Plasmid (Human) - CHH0991 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRYAA miRNA 3'UTR clone - MiUTR1H-02443 from Creative biogene

Species Reactivities Human
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