Gene Symbol |
Lbp
|
Entrez Gene |
16803
|
Alt Symbol |
Bpifd2, Ly88
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
lipopolysaccharide binding protein
|
Other Description |
lipopolysaccharide-binding protein
|
Swissprots |
Q99KA0 A2AC66 Q61805
|
Accessions |
EDL06262 Q61805 AA207419 AI643881 AJ010499 AJ010736 AK143562 AK158105 BC004795 AAH04795 BQ176753 X99347 CAA67727 NM_008489 NP_032515
|
Function |
Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted.
|
Top Pathways |
Toll-like receptor signaling pathway, Salmonella infection, Tuberculosis
|