Gene Symbol | Lbp |
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Entrez Gene | 16803 |
Alt Symbol | Bpifd2, Ly88 |
Species | Mouse |
Gene Type | protein-coding |
Description | lipopolysaccharide binding protein |
Other Description | lipopolysaccharide-binding protein |
Swissprots | Q99KA0 A2AC66 Q61805 |
Accessions | EDL06262 Q61805 AA207419 AI643881 AJ010499 AJ010736 AK143562 AK158105 BC004795 AAH04795 BQ176753 X99347 CAA67727 NM_008489 NP_032515 |
Function | Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | Toll-like receptor signaling pathway, Salmonella infection, Tuberculosis |
LBP CRISPR/Cas9 KO Plasmid (m) - sc-421393 from Santa Cruz Biotechnology
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LBP HDR Plasmid (m) - sc-421393-HDR from Santa Cruz Biotechnology
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LBP Double Nickase Plasmid (m) - sc-421393-NIC from Santa Cruz Biotechnology
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LBP Double Nickase Plasmid (m2) - sc-421393-NIC-2 from Santa Cruz Biotechnology
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LBP CRISPR Activation Plasmid (m) - sc-421393-ACT from Santa Cruz Biotechnology
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LBP CRISPR Activation Plasmid (m2) - sc-421393-ACT-2 from Santa Cruz Biotechnology
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LBP Lentiviral Activation Particles (m) - sc-421393-LAC from Santa Cruz Biotechnology
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LBP Lentiviral Activation Particles (m2) - sc-421393-LAC-2 from Santa Cruz Biotechnology
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LBP siRNA (m) - sc-146662 from Santa Cruz Biotechnology
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LBP shRNA Plasmid (m) - sc-146662-SH from Santa Cruz Biotechnology
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LBP shRNA (m) Lentiviral Particles - sc-146662-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU080121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34642 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34642 from Sigma-Aldrich
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LBP siRNA (Mouse) - CRM2311 from Cohesion Biosciences
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shRNA set against Mouse LBP (NM_008489.2) - SHH328739 from Creative biogene
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shRNA set against Mouse Lbp(NM_008489.2) - SHH143435 from Creative biogene
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Mouse LBP siRNA - orb281787 from Biorbyt
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LBP shRNA Plasmid (Mouse) - CHM2311 from Cohesion Biosciences
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LBP miRNA 3'UTR clone - MiUTR1M-06540 from Creative biogene
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