| Gene Symbol |
Hsd17b11
|
| Entrez Gene |
289456
|
| Alt Symbol |
Dhrs8
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
hydroxysteroid (17-beta) dehydrogenase 11
|
| Other Description |
17-beta-HSD 11|17-beta-HSD XI|17-beta-hydroxysteroid dehydrogenase 11|17-beta-hydroxysteroid dehydrogenase XI|17bHSD11|17betaHSD11|17betaHSDXI|dehydrogenase/reductase (SDR family) member 8|dehydrogenase/reductase SDR family member 8|estradiol 17-beta-dehydrogenase 11
|
| Swissprots |
Q6AYS8
|
| Accessions |
EDL99508 EDL99509 EDL99510 Q6AYS8 BC078929 AAH78929 FQ210820 FQ211398 FQ222122 XM_006250627 XP_006250689 XM_006250629 XP_006250691 NM_001004209 NP_001004209
|
| Function |
Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|