| Gene Symbol | Hsd17b11 |
|---|---|
| Entrez Gene | 289456 |
| Alt Symbol | Dhrs8 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | hydroxysteroid (17-beta) dehydrogenase 11 |
| Other Description | 17-beta-HSD 11|17-beta-HSD XI|17-beta-hydroxysteroid dehydrogenase 11|17-beta-hydroxysteroid dehydrogenase XI|17bHSD11|17betaHSD11|17betaHSDXI|dehydrogenase/reductase (SDR family) member 8|dehydrogenase/reductase SDR family member 8|estradiol 17-beta-dehydrogenase 11 |
| Swissprots | Q6AYS8 |
| Accessions | EDL99508 EDL99509 EDL99510 Q6AYS8 BC078929 AAH78929 FQ210820 FQ211398 FQ222122 XM_006250627 XP_006250689 XM_006250629 XP_006250691 NM_001004209 NP_001004209 |
| Function | Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted {ECO:0000305}. |
CompoZr® Knockout ZFN Kit - CKOZFN55209 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND55209 from Sigma-Aldrich
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HSD17B11 siRNA (Rat) - CRR4044 from Cohesion Biosciences
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HSD17B11 - MBS8201086 from MyBioSource
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shRNA set against Rat HSD17B11 (NM_001004209.1) - SHH315165 from Creative biogene
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HSD17B11 shRNA Plasmid (Rat) - CHR4044 from Cohesion Biosciences
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HSD17B11 miRNA 3'UTR clone - MiUTR1R-01488 from Creative biogene
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