HSD3B2

Gene Symbol HSD3B2
Entrez Gene 3284
Alt Symbol HSD3B, HSDB, SDR11E2
Species Human
Gene Type protein-coding
Description hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Other Description 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II|3-beta-HSD II|3-beta-HSD adrenal and gonadal type|3-beta-hydroxy-5-ene steroid dehydrogenase|3-beta-hydroxy-Delta(5)-steroid dehydrogenase|delta 5-delta 4-isomerase type II|progesterone reductase|short chain dehydrogenase/reductase family 11E, member 2
Swissprots Q9UD08 Q6AI10 A2RRA5 Q53GD4 P26439 Q16010 Q99890 Q6LDB9
Accessions AAA36014 AAC60599 AAC60600 AAD14930 AJF45348 EAW56700 EAW56701 EAW56702 P26439 AK222997 BAD96717 AK313413 BAG36207 AV705363 BC038419 AAH38419 BC131488 AAI31489 BP197992 CF596786 DQ891764 ABM82690 DQ894948 ABM85874 M67466 AAA36016 NM_000198 NP_000189 NM_001166120 NP_001159592
Function 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Subcellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Tissue Specificity Expressed in adrenal gland, testis and ovary.
Top Pathways Steroid hormone biosynthesis, Ovarian steroidogenesis

Human HSD3B2 full length protein - ab114766 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE Stained with Coomassie Blue showing ab114766 at approximately 66.99kDa.

Human HSD3B2 protein fragment - ab114767 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE Stained with Coomassie Blue showing ab114767 at approximately 35.53kDa.

HSD3B2 Antibody Blocking Peptide - LS-E16249 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Beta Hydroxysteroid Dehydrogenase Protein - H00003284-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Beta Hydroxysteroid Dehydrogenase Partial Recombinant Protein - H00003284-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

HSD3B2-Antibody-C-term-Blocking-Peptide - BP18318b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

HSD3B2-Antibody-N-term-Blocking-Peptide - BP6761a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

HSD3B2 Blocking Peptide - 33R-3671 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

3-beta HSD2 / HSD3B2 - H00003284-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

3-beta HSD2 / HSD3B2 - H00003284-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

3-beta HSD2 / HSD3B2 - H00003284-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

3-beta HSD2 / HSD3B2 - H00003284-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

HSD3B2 fusion protein - ag7782 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

HSD3B2 fusion protein - ag4291 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human HSD3B2 - HSD3B2-29343TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human HSD3B2 - HSD3B2-29345TH from Creative Biomart

Category Protein
Source Wheat germ

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2), Recombinant Protein - MBS957764 from MyBioSource

Category Protein
Prices $1,375.00, $1,835.00
Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

3-beta HSD2 / HSD3B2 - TP306593 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
3-beta HSD2 / HSD3B2

3-beta HSD2 / HSD3B2 (transcript variant 2) - TP328855 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
3-beta HSD2 / HSD3B2

HSD3B2 Blocking Peptide - abx061608 from Abbexa

Category Peptide

HSD3B2 Peptide, Human - M34GP07287H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

HSD3B2 Blocking Peptide - CBP5295 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2), Recombinant Protein - MBS7016797 from MyBioSource

Category Protein
Prices $1,180.00, $2,165.00, $3,370.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human

Recombinant Human HSD3B2 Protein, Myc/DDK-tagged - HSD3B2-001H from Creative Biomart

Category Protein
Source HEK293T
Species Human

Recombinant Human HSD3B2 Protein, Myc/DDK-tagged - HSD3B2-002H from Creative Biomart

Category Protein
Source HEK293T
Species Human
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