TRPC1

Gene Symbol TRPC1
Entrez Gene 7220
Alt Symbol HTRP-1, TRP1
Species Human
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily C, member 1
Other Description TRP-1|capacitative calcium channel protein Trp1|short transient receptor potential channel 1|transient receptor potential canonical 1|transient receptor protein 1
Swissprots Q14CE4 P48995
Accessions CAJ01296 EAW78963 EAW78964 P48995 AB255425 BAF76425 AF483645 AAM97860 AI280444 BC112338 AAI12339 BC113953 AAI13954 BX331349 DB185459 EF522961 ABP94017 GQ293239 ACT66710 X89066 CAA61447 XM_005247738 XP_005247795 XM_005247739 XP_005247796 XR_241506 XR_924164 XR_924165 XR_924166 NM_001251845 NP_001238774 NM_003304 NP_003295
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. {ECO:0000269|PubMed:15016832}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Seems to be ubiquitous.
Top Pathways Pancreatic secretion, Glutamatergic synapse

TRPC1 (E-6) - sc-133076 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRPC1 (E-6): sc-133076. Western blot analysis of TRPC1 expression in SH-SY5Y whole cell lysate.

TRPC1 (C-14) - sc-15055 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRPC1 (C-14): sc-15055. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells.

TRPC1 (H-105) - sc-20110 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRPC1 (H-105): sc-20110. Western blot analysis of TRPC1 expression in rat testis (A) and mouse testis (B) tissue extracts.

TRPC1 (A-14) - sc-23011 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TRPC1 [EPR1417(2)] antibody - ab192031 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1417(2)
All lanes : Anti-TRPC1 [EPR1417(2)] antibody (ab192031) at 1/10000 dilutionLane 1 : SH-SY5Y lysateLane 2 : HepG2 lysateLane 3 : Caco-2 lysateLane 4 : Human testis lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-TRPC1 antibody - ab74819 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab74819 (1/500) staining TRPC1 in rat brain tissue by Immunohistochemistry (frozen). DAPI counterstaining appears in blue.

Anti-TRPC1 antibody - ab75322 from Abcam

Prices $382.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 antibody - ab63074 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-TRPC1 antibody - ab84160 from Abcam

Host Sheep
Clonality Polyclonal

Anti-TRPC1 antibody - ab110837 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab110837 at 3.75 &microg/ml staining TRPC1 in Human cortex by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-TRPC1 antibody [EP1417Y] - ab51255 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1417Y
Anti-TRPC1 antibody [EP1417Y] (ab51255) at 1/10000 dilution + HepG2 cell lysate at 10 µgSecondaryGoat anti-Rabbit HRP labeled at 1/2000 dilution

Anti-TRPC1 Antibody (aa700-750) - LS-C94998 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody - LS-C95218 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (2nd Extracellular Domain) - LS-C136510 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-TRPC1 Antibody (C-Terminus) - LS-C153552 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (C-Terminus) - LS-C144822 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793, APC) - LS-C272295 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793, AP) - LS-C272294 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793, Biotin) - LS-C272296 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793, FITC) - LS-C272297 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793, Azide-free, HRP) - LS-C272298 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793, PE) - LS-C272300 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa764-793) - LS-C325981 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC1 Antibody (aa765-793) - LS-C160227 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TRPC1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The TRPC1 antibody detected the TRPC1 protein (arrow).

Anti-TRPC1 Antibody (clone 1E4) - LS-C198370 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E4
Detection limit for recombinant GST tagged TRPC1 is 0.1 ng/ml as a capture antibody.
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