| Gene Symbol |
TRPC1
|
| Entrez Gene |
7220
|
| Alt Symbol |
HTRP-1, TRP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transient receptor potential cation channel, subfamily C, member 1
|
| Other Description |
TRP-1|capacitative calcium channel protein Trp1|short transient receptor potential channel 1|transient receptor potential canonical 1|transient receptor protein 1
|
| Swissprots |
Q14CE4 P48995
|
| Accessions |
CAJ01296 EAW78963 EAW78964 P48995 AB255425 BAF76425 AF483645 AAM97860 AI280444 BC112338 AAI12339 BC113953 AAI13954 BX331349 DB185459 EF522961 ABP94017 GQ293239 ACT66710 X89066 CAA61447 XM_005247738 XP_005247795 XM_005247739 XP_005247796 XR_241506 XR_924164 XR_924165 XR_924166 NM_001251845 NP_001238774 NM_003304 NP_003295
|
| Function |
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. {ECO:0000269|PubMed:15016832}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Seems to be ubiquitous.
|
| Top Pathways |
Pancreatic secretion, Glutamatergic synapse
|