CDC27

Gene Symbol	CDC27
Entrez Gene	996
Alt Symbol	ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, H-NUC, HNUC, NUC2
Species	Human
Gene Type	protein-coding
Description	cell division cycle 27
Other Description	anaphase promoting complex subunit 3|anaphase-promoting complex, protein 3|cell division cycle 27 homolog|cell division cycle protein 27 homolog|nuc2 homolog
Swissprots	Q96F35 G3V1C4 Q16349 P30260
Accessions	AAR89911 AFI24904 AFI24906 AFI24908 EAW57686 EAW57687 EAW57688 EAW57689 P30260 AA927469 AK296881 BAG59442 AK299342 BAG61343 AU135593 BC011656 AAH11656 BI548077 BP234964 DQ786193 DQ892780 ABM83706 DQ896027 ABM87026 HY023336 S78234 AAB34378 U00001 AAA60471 XM_011525546 XP_011523848 XM_011525547 XP_011523849 XM_011525548 XP_011523850 XM_011525549 XP_011523851 XM_011525550 XP_011523852 XR_934630 NM_001114091 NP_001107563 NM_001256 NP_001247 NM_001293089 NP_001280018 NM_001293091 NP_001280020
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
Subcellular Location	Nucleus.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® APC3 siRNA I - 11821 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

Cdc27 CRISPR/Cas9 KO Plasmid (h) - sc-400789 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 HDR Plasmid (h) - sc-400789-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 Double Nickase Plasmid (h) - sc-400789-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 Double Nickase Plasmid (h2) - sc-400789-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 CRISPR Activation Plasmid (h) - sc-400789-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 CRISPR Activation Plasmid (h2) - sc-400789-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 Lentiviral Activation Particles (h) - sc-400789-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 Lentiviral Activation Particles (h2) - sc-400789-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc27 siRNA (h) - sc-77362 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Cdc27 shRNA Plasmid (h) - sc-77362-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Cdc27 shRNA (h) Lentiviral Particles - sc-77362-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU004241 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5777 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5777 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05918 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05918

CDC27 siRNA (Human) - CRH0710 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CDC27 - MBS8228698 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CDC27(NM_001256.3) - SHG160903 from Creative biogene Category siRNA Species Reactivities Human

CDC27 shRNA Plasmid (Human) - CHH0710 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CDC27 miRNA 3'UTR clone - MiUTR1H-01939 from Creative biogene Species Reactivities Human

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