RAN

Gene Symbol	RAN
Entrez Gene	5901
Alt Symbol	ARA24, Gsp1, TC4
Species	Human
Gene Type	protein-coding
Description	RAN, member RAS oncogene family
Other Description	GTP-binding nuclear protein Ran|GTPase Ran|OK/SW-cl.81|RanGTPase|androgen receptor-associated protein 24|guanosine triphosphatase Ran|member RAS oncogene family|ras-like protein TC4|ras-related nuclear protein
Swissprots	Q8NI90 A8K3Z8 Q6IPB2 P62826
Accessions	AAB24940 EAW98515 EAW98516 EAW98517 P62826 AB062399 BAB93486 AF052578 AAC05840 AF054183 AAC99400 AF501887 AAM15923 AK300934 BAG62563 AK311223 AK312466 BAG35373 AK316193 BAH14564 AL357616 BC000852 BC004272 AAH04272 BC014518 AAH14518 BC014901 AAH14901 BC016654 AAH16654 BC022813 BC051908 AAH51908 BC072000 AAH72000 BT007271 AAP35935 CR450347 CAG29343 DQ892358 ABM83284 DQ895565 ABM86491 HY139187 HY336901 M31469 AAA36546 NM_001300796 NP_001287725 NM_001300797 NP_001287726 NM_006325 NP_006316
Function	GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. {ECO:0000250}.
Subcellular Location	Nucleus. Cytoplasm. Melanosome. Note=Predominantly nuclear during interphase (By similarity). Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250}.
Tissue Specificity	Expressed in a variety of tissues. {ECO:0000269|PubMed:2108320}.
Top Pathways	RNA transport, Ribosome biogenesis in eukaryotes, HTLV-I infection, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Ran (mutated E70 A) full length protein - ab90203 from Abcam Category Protein Source E. coli Species Human

Human Ran (mutated G19 V + Q69 L) protein fragment - ab90724 from Abcam Category Protein Source E. coli Species Human

Human Ran (mutated Q69 L) full length protein - ab176633 from Abcam Category Protein Source E. coli Species Human

Human Ran (mutated Q69 L) full length protein - ab90208 from Abcam Category Protein Source E. coli Species Human

Human Ran (mutated T24 N) full length protein - ab90206 from Abcam Category Protein Source E. coli Species Human

Human Ran full length protein - ab176629 from Abcam Category Protein Source E. coli Species Human

Human Ran full length protein - ab59309 from Abcam Category Protein Source E. coli Species Human

Human Ran peptide - ab23304 from Abcam Category Peptide Species Human

RAN Antibody Blocking Peptide - LS-E25740 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAN Antibody Blocking Peptide - LS-E27584 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAN Antibody Blocking Peptide - LS-E8389 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAN Antibody Blocking Peptide - LS-E8390 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Ran Protein - H00005901-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Source Wheat Germ Species Human

Ran Recombinant Protein - H00005901-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Ran Protein - NBP1-45255 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

RAN-Antibody-Center-Blocking-Peptide - BP6693b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAN-Antibody-N-term-Blocking-Peptide - BP6693a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAN-Antibody-Center-Blocking-Peptide - BP6825c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAN-Antibody-N-term-Blocking-Peptide - BP6825a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAN blocking peptide - GTX17033-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

RAN Protein (OPPA02353) - OPPA02353 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human RAN protein - orb81303 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

RAB27A protein (His tag) - 80R-1320 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

RAB3A protein (His tag) - 80R-1864 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

RAB6B protein (His tag) - 80R-1676 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

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