GSN

Gene Symbol	GSN
Entrez Gene	2934
Alt Symbol	ADF, AGEL
Species	Human
Gene Type	protein-coding
Description	gelsolin
Other Description	actin-depolymerizing factor|brevin
Swissprots	B7Z5V1 Q8WVV7 Q5T0I2 A8MUD1 B7Z373 F5H1A8 P06396 A8MYN7 A2A418
Accessions	CAA30101 CAA30102 EAW87489 EAW87490 EAW87491 P06396 AI742454 AK092797 BAG52611 AK096280 BAG53247 AK125819 BAG54252 AK295201 BAH12010 AK295572 BAH12109 AK297870 BAH12682 AK299453 BAH13037 AK300631 BAH13318 AK304629 BAH14228 AK304675 BAH14236 AK307859 AK315494 BAG37878 AL832070 CAH10407 BC017491 AAH17491 BC026033 AAH26033 BU151663 BX647999 DA294394 DA394782 DA450851 DA823796 DB170452 DB250757 DC316173 DC341948 DC370937 DC378873 DQ892187 ABM83113 EU176693 ABW03494 X04412 CAA28000 XM_005251940 XP_005251997 XM_005251943 XP_005252000 XM_005251944 XP_005252001 XM_005251945 XP_005252002 XM_006717075 XP_006717138 XM_006717079 XP_006717142 XM_011518584 XP_011516886 XM_011518585 XP_011516887 XM_011518586 XP_011516888 XM_011518587 XP_011516889 XM_011518588 XP_011516890 XM_011518589 XP_011516891 XM_011518590 XP_011516892 XM_011518591 XP_011516893 XM_011518592 XP_011516894 XM_011518593 XP_011516895 XM_011518594 XP_011516896 NM_000177 NP_000168 NM_001127662 NP_001121134 NM_001127663 NP_001121135 NM_001127664 NP_001121136 NM_001127665 NP_001121137 NM_001127666 NP_001121138 NM_001127667 NP_001121139 NM_001258029 NP_001244958 NM_001258030 NP_001244959 NM_198252 NP_937895
Function	Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. {ECO:0000269|PubMed:20393563}.
Subcellular Location	Isoform 2: Cytoplasm, cytoskeleton.
Tissue Specificity	Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.
Top Pathways	Fc gamma R-mediated phagocytosis, Viral carcinogenesis, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

GSN 293T Cell Transient Overexpression Lysate(Denatured) - H00002934-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

GSN overexpression lysate - LY424875 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GSN 293 Cell Lysate - 410304 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Gelsolin/GSN Overexpression Lysate (Denatured) - H00002934-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Gelsolin (h2): 293T Lysate - sc-171065 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

GSN Over-expression Lysate Product - GWB-2435DF from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Gelsolin/GSN Overexpression Lysate (Native) - NBP2-11156 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

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