| Gene Symbol |
ATP5B
|
| Entrez Gene |
327675
|
| Alt Symbol |
-
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
|
| Other Description |
ATP synthase subunit beta, mitochondrial|F1-ATPase beta-subunit|mitochondrial ATP synthase beta subunit
|
| Swissprots |
Q9T2U5 Q1JQA9 P00829 Q9T2U4
|
| Accessions |
DAA29742 P00829 BC116099 AAI16100 DQ403115 ABD77248 M20929 AAA30395 X05605 CAA29094 NM_175796 NP_786990
|
| Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
|
| Subcellular Location |
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Oxidative phosphorylation
|