CHRNA4

Gene Symbol CHRNA4
Entrez Gene 1137
Alt Symbol BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, alpha 4 (neuronal)
Other Description cholinergic receptor, nicotinic, alpha polypeptide 4|neuronal acetylcholine receptor subunit alpha-4|neuronal nicotinic acetylcholine receptor alpha-4 subunit
Swissprots Q4VAQ5 Q4JGR7 P43681 Q4VAQ6
Accessions AAV66461 AAW81038 AAW81039 AAY88737 EAW75269 EAW75270 P43681 AK296430 BAG59090 AK314907 BC096290 AAH96290 BC096291 AAH96291 BC096292 AAH96292 BC096293 AAH96293 BM710937 DA530118 L35901 AAA64743 U62433 AAB40111 X87629 CAA60959 X89741 CAA61893 X89742 X89743 X89744 X89745 X89746 Y08421 CAA69698 XM_011528524 XP_011526826 NM_000744 NP_000735 NM_001256573 NP_001243502 NR_046317
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. {ECO:0000269|PubMed:22361591}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Top Pathways Nicotine addiction, Neuroactive ligand-receptor interaction

AChRα4 (A-6) - sc-74519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AChRα4 (A-6): sc-74519. Immunofluorescence staining of formalin-fixed Hep G2 cells showing cytoplasmic localization.

AChRα4 (A-20) - sc-1772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AChRα4 (A-20): sc-1772. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

AChRα4 (H-133) - sc-5591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AChRα4 (H-133): sc-5591. Western blot analysis of AChRα4 expression in Sol8 (A) and PC-12 (B) whole cell lysates.

AChRα4 (299) - sc-65862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody - ab88239 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody (ab88239) at 1 µg/mlLane 1 : SW480 (Human colon adenocarcinoma cell line) Whole Cell LysateLane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 3 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 4 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 5 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody - ab167556 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody (ab167556) at 1 µg/mlLane 1 : Nicotinic Acetylcholine Receptor alpha 4 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.

Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody [EPR4563(2)] - ab124832 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4563(2)
All lanes : Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody [EPR4563(2)] (ab124832) at 1/10000 dilutionLane 1 : SH-SY5Y cell lysateLane 2 : A673 cell lysateLane 3 : C6 cell lysateLane 4 : Neuro-2a cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CHRNA4 / NACHR Antibody (aa568-588) - LS-C37652 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µl
Host Guinea Pig
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (aa620-627) - LS-C37655 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (Internal) - LS-C61722 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (C-Terminus) - LS-C73542 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (C-Terminus) - LS-C73543 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (C-Terminus) - LS-C73544 from LifeSpan Bioscience

Prices $515.00
Sizes 5 ml
Host Rabbit
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (aa29-128) - LS-C124828 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CHRNA4 / NACHR Antibody (Extracellular Domain) - LS-C126027 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (aa1-451) - LS-C131052 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (clone 8A4) - LS-C195686 from LifeSpan Bioscience

Prices $560.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 8A4

Anti-CHRNA4 / NACHR Antibody (clone 4E3) - LS-C196914 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E3

Anti-CHRNA4 / NACHR Antibody (N-Terminus) - LS-C112320 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CHRNA4 antibody LS-C112320 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-CHRNA4 / NACHR Antibody - LS-C307793 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CHRNA4 / NACHR Antibody (aa36-85) - LS-C101526 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CHRNA4 antibody LS-C101526 Western blot of HepG2 cell lysate.

Anti-CHRNA4 / NACHR Antibody (Internal) - LS-C112799 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CHRNA4 antibody (0.3 ug/ml) staining of Rat Brain lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CHRNA4 / NACHR Antibody (Internal, clone EPR4563(2)) - LS-C138304 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4563(2)
Western blot analysis on (A) SH-SY5Y, (B) A673, (C) C6, and (D) Neuro-2a cell lysates using anti-ACHR-alpha 4 antibody.

Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody - NBP1-80057 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Nicotinic Acetylcholine Receptor alpha 4 Antibody [NBP1-80057] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody - NBP1-79947 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Nicotinic Acetylcholine Receptor alpha 4 Antibody [NBP1-79947] - HepG2 cell lysate, concentration 0.2-1 ug/ml.
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