CHRNA4

Gene Symbol CHRNA4
Entrez Gene 1137
Alt Symbol BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, alpha 4 (neuronal)
Other Description cholinergic receptor, nicotinic, alpha polypeptide 4|neuronal acetylcholine receptor subunit alpha-4|neuronal nicotinic acetylcholine receptor alpha-4 subunit
Swissprots Q4VAQ5 Q4JGR7 P43681 Q4VAQ6
Accessions AAV66461 AAW81038 AAW81039 AAY88737 EAW75269 EAW75270 P43681 AK296430 BAG59090 AK314907 BC096290 AAH96290 BC096291 AAH96291 BC096292 AAH96292 BC096293 AAH96293 BM710937 DA530118 L35901 AAA64743 U62433 AAB40111 X87629 CAA60959 X89741 CAA61893 X89742 X89743 X89744 X89745 X89746 Y08421 CAA69698 XM_011528524 XP_011526826 NM_000744 NP_000735 NM_001256573 NP_001243502 NR_046317
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. {ECO:0000269|PubMed:22361591}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Top Pathways Nicotine addiction, Neuroactive ligand-receptor interaction

AChRα4 CRISPR/Cas9 KO Plasmid (h) - sc-401605 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 HDR Plasmid (h) - sc-401605-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 Double Nickase Plasmid (h) - sc-401605-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 Double Nickase Plasmid (h2) - sc-401605-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 CRISPR Activation Plasmid (h) - sc-401605-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 CRISPR Activation Plasmid (h2) - sc-401605-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 Lentiviral Activation Particles (h) - sc-401605-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 Lentiviral Activation Particles (h2) - sc-401605-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα4 siRNA (h) - sc-42528 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AChRα4 shRNA Plasmid (h) - sc-42528-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AChRα4 shRNA (h) Lentiviral Particles - sc-42528-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nicotinic Acetylcholine R alpha 4/CHRNA4 RNAi - H00001137-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN1791 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1791 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR14071 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr14071

CHRNA4 siRNA (Human) - CRH0814 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHRNA4 - MBS8204603 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHRNA4 (NM_000744.6) - SHH263561 from Creative biogene

Category siRNA
Species Reactivities Human

CHRNA4 shRNA Plasmid (Human) - CHH0814 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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