ABCB6

Gene Symbol ABCB6
Entrez Gene 10058
Alt Symbol ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
Other Description ATP-binding cassette half-transporter|ATP-binding cassette sub-family B member 6, mitochondrial|P-glycoprotein-related protein|mitochondrial ABC transporter 3|mt-ABC transporter 3|ubiquitously-expressed mammalian ABC half transporter
Swissprots Q9HAQ7 Q59GQ5 Q6ZME6 Q9HAQ6 Q49A66 O75542 Q96ME8 Q9NP58
Accessions AAG33618 BAA96733 BAN91499 BAN91500 BAN91501 BAN91502 BAN91503 BAN91504 EAW70694 EAW70695 EAW70696 EAW70697 EAW70698 EAW70699 EAW70700 EAW70701 EAW70702 EAW70703 EAW70704 EAW70705 Q9NP58 AF070598 AAC28653 AF076775 AAF75107 AF308472 AAG33617 AJ289233 CAB95766 AK026067 AK057026 BAB71347 AK172812 BAD18782 AK303230 BAG64317 AL560811 AW664349 BC000559 AAH00559 BC043423 AAH43423 DQ891876 ABM82802 DQ895063 ABM85989 U66673 NM_005689 NP_005680
Function Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:17006453}.
Subcellular Location Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Endosome {ECO:0000250}. Note=localized to the endosome- like compartement and dendrite tips.
Tissue Specificity Widely expressed. High expression is detected in the retinal epithelium. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:22226084}.
Top Pathways ABC transporters

ABCB6 overexpression lysate - LY417131 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ABCB6 Overexpression Lysate (Native) - NBP2-07717 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ABCB6 Overexpression Lysate (Adult Normal) [NBP2-07717] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABCB6.

Panoply™ Human ABCB6 Knockdown Stable Cell Line - CSC-DC000045 from Creative biogene

Category Cell Line
Species Human
Search more