ABCB6

Gene Symbol ABCB6
Entrez Gene 10058
Alt Symbol ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
Other Description ATP-binding cassette half-transporter|ATP-binding cassette sub-family B member 6, mitochondrial|P-glycoprotein-related protein|mitochondrial ABC transporter 3|mt-ABC transporter 3|ubiquitously-expressed mammalian ABC half transporter
Swissprots Q9HAQ7 Q59GQ5 Q6ZME6 Q9HAQ6 Q49A66 O75542 Q96ME8 Q9NP58
Accessions AAG33618 BAA96733 BAN91499 BAN91500 BAN91501 BAN91502 BAN91503 BAN91504 EAW70694 EAW70695 EAW70696 EAW70697 EAW70698 EAW70699 EAW70700 EAW70701 EAW70702 EAW70703 EAW70704 EAW70705 Q9NP58 AF070598 AAC28653 AF076775 AAF75107 AF308472 AAG33617 AJ289233 CAB95766 AK026067 AK057026 BAB71347 AK172812 BAD18782 AK303230 BAG64317 AL560811 AW664349 BC000559 AAH00559 BC043423 AAH43423 DQ891876 ABM82802 DQ895063 ABM85989 U66673 NM_005689 NP_005680
Function Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:17006453}.
Subcellular Location Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Endosome {ECO:0000250}. Note=localized to the endosome- like compartement and dendrite tips.
Tissue Specificity Widely expressed. High expression is detected in the retinal epithelium. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:22226084}.
Top Pathways ABC transporters

ABCB6 CRISPR/Cas9 KO Plasmid (h) - sc-403817 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 HDR Plasmid (h) - sc-403817-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 Double Nickase Plasmid (h) - sc-403817-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 Double Nickase Plasmid (h2) - sc-403817-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 CRISPR Activation Plasmid (h) - sc-403817-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 CRISPR Activation Plasmid (h2) - sc-403817-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 Lentiviral Activation Particles (h) - sc-403817-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 Lentiviral Activation Particles (h2) - sc-403817-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB6 siRNA (h) - sc-94721 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB6 shRNA Plasmid (h) - sc-94721-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB6 shRNA (h) Lentiviral Particles - sc-94721-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB6 RNAi - H00010058-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU079651 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2629 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2629 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ABCB6 siRNA (Human) - CRH6774 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCB6 - MBS8226576 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ABCB6 (NM_005689.2) - SHH229022 from Creative biogene

Category siRNA
Species Reactivities Human

Human ABCB6 siRNA - orb267276 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCB6 shRNA Plasmid (Human) - CHH6774 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCB6 miRNA 3'UTR clone - MiUTR3H-07685 from Creative biogene

Species Reactivities Human
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