Lta

Gene Symbol	Lta
Entrez Gene	16992
Alt Symbol	LT, LT-[a], LT-alpha, LT[a], LTalpha, Ltx, TNF-beta, TNFSF1, Tnfb, Tnfsf1b, hlb382
Species	Mouse
Gene Type	protein-coding
Description	lymphotoxin A
Other Description	TNF beta|lymphotoxin alpha|lymphotoxin-alpha|tumor necrosis factor ligand superfamily member 1
Swissprots	P09225
Accessions	AAA18593 AAA39450 AAA40461 AAC82485 CAA29566 CAA29567 CAA68330 CAA68529 EDL26629 EDL26630 P09225 AK080308 BAC37874 AK153694 BAE32147 AK156659 BAE33797 BC099464 AAH99464 M16819 AAA40460 X14800 CAA32906 XM_006523731 XP_006523794 XM_006525331 XP_006525394 XM_006536550 XP_006536613 XM_006537284 XP_006537347 NM_010735 NP_034865
Function	Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Subcellular Location	Secreted {ECO:0000250}. Membrane {ECO:0000250}. Note=The homotrimer is secreted. The heterotrimer is membrane-associated. {ECO:0000250}.
Top Pathways	Cytokine-cytokine receptor interaction, Type I diabetes mellitus, HTLV-I infection, Herpes simplex infection, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse TNFb Protein - abx069539 from Abbexa Category Protein Source E.coli Species Mouse

TNF-beta (E.coli-derived), Human, Recombinant - 28-10326 from ARP American Research Products Category Protein Prices $99.00, $102.00, $199.00 Sizes 5 µg, 1 mg, 20 µg Source E. Coli Species Mouse

Tumor Necrosis Factor Beta (TNFb), Mouse - 20-6326 from ARP American Research Products Category Protein Prices $469.00 Sizes 50 µg Source E.coli Species Mouse

Mouse Tumour Necrosis Factor alpha (rDNA derived) Reference standard - Lta-90M from Creative Biomart Category Protein Species Mouse

Recombinant Tumor Necrosis Factor Beta (TNFb) - RPA134Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Tumor Necrosis Factor Beta (TNFb) - RPA134Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Lymphotoxin-alpha(Lta) - CSB-YP013218MO CSB-EP013218MO CSB-BP013218MO CSB-MP013218MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse LTA Protein - LTA-9342M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

LTA Recombinant Protein (OPCD07551) - OPCD07551 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Lymphotoxin-alpha (Lta), Recombinant Protein - MBS948127 from MyBioSource Category Protein Prices $808.00, $808.00, $915.00, $915.00, $1,330.00, $1,330.00, $1,790.00, $1,790.00, $1,790.00, $2,620.00 Sizes 50 µg (Mammalian-Cell), 500 µg (Yeast), 500 µg (E-Coli), 50 µg (Baculovirus), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Recombinant Mouse Lymphotoxin-alpha (Lta) - RPC21627 from Biomatik Category Protein Prices $276.00, $505.00, $2,491.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Mouse

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