CACNA1D

Gene Symbol	CACNA1D
Entrez Gene	776
Alt Symbol	CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, PASNA, SANDD
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, L type, alpha 1D subunit
Other Description	calcium channel, L type, alpha-1 polypeptide|calcium channel, neuroendocrine/brain-type, alpha 1 subunit|voltage-dependent L-type calcium channel subunit alpha-1D|voltage-gated calcium channel alpha 1 subunit|voltage-gated calcium channel alpha subunit Cav1.3
Swissprots	Q71UT1 Q13916 Q9UDC3 Q01668 Q13931 B0FYA3
Accessions	AAD08651 BAA07804 EAW65286 EAW65287 EAW65288 EAW65289 EAW65290 EAW65291 EAW65292 EAW65293 EAW65294 EAW65295 Q01668 AB209171 BAD92408 AK294397 BAH11755 AK294585 BAG57776 AW008794 EU363339 ABY66526 M76558 AAA58402 M83566 AAA35629 XM_005265448 XP_005265505 XM_011534094 XP_011532396 XM_011534095 XP_011532397 XM_011534096 XP_011532398 XM_011534097 XP_011532399 XM_011534098 XP_011532400 XM_011534099 XP_011532401 XM_011534100 XP_011532402 NM_000720 NP_000711 NM_001128839 NP_001122311 NM_001128840 NP_001122312
Function	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin- GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). {ECO:0000269|PubMed:18482979}.
Subcellular Location	Membrane {ECO:0000269|PubMed:18482979}; Multi-pass membrane protein {ECO:0000269|PubMed:18482979}.
Tissue Specificity	Expressed in pancreatic islets and in brain, where it has been seen in cerebral cortex, hippocampus, basal ganglia, habenula and thalamus. Expressed in the small cell lung carcinoma cell line SCC-9. No expression in skeletal muscle. {ECO:0000269|PubMed:1335101}.
Top Pathways	Oxytocin signaling pathway, Calcium signaling pathway, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Circadian entrainment

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CACNA1D / Cav1.3 ELISA Kit (Sandwich ELISA) - LS-F7587 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.121 ng/ml Range 0.313-20 ng/ml

Mouse CACNA1D / Cav1.3 ELISA Kit (Sandwich ELISA) - LS-F8774 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 0.313-20 ng/ml

Human CACNa1D ELISA Kit - abx150887 from Abbexa Category ELISA Kit Sensitivity 0.121 ng/ml Range 0.313 ng/ml - 20 ng/ml

Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D), Human, ELISA Kit - SEF237Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.121ng/mL Range 0.312-20ng/mL

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), Human, ELISA Kit - E01V0058 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D), ELISA Kit - MBS2024209 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.121ng/mL. Range 0.313-20ng/mL

Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D), ELISA Kit - MBS2019626 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.113ng/mL. Range 0.313-20ng/mL

Voltage dependent L type calcium channel subunit Alpha 1D (CACNA1D), ELISA Kit - MBS7243703 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit Alpha 1D (CACNA1D), ELISA Kit - MBS7218681 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7225164 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7244383 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7219070 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7253645 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7212448 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7207865 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7202765 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7249120 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), ELISA Kit - MBS7244262 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) - SEF237Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.121ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) - SEF237Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) - SEF237Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.121ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D), Human, ELISA Kit - DL-CACNa1D-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human CACNa1D ELISA Kit - abx572591 from Abbexa Category ELISA Kit Sensitivity 0.121 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human CACNA1D ELISA Kit - E006018 from Biobool Category ELISA Kit Sensitivity Typically less than 0.121ng/mL.

CACNA1D ELISA Kit (Human) (OKCD01855) - OKCD01855 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.121 ng/mL Range 0.312 - 20 ng/mL

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