Gene Symbol | TCIRG1 |
---|---|
Entrez Gene | 10312 |
Alt Symbol | ATP6N1C, ATP6V0A3, Atp6i, OC-116kDa, OC116, OPTB1, Stv1, TIRC7, Vph1, a3 |
Species | Human |
Gene Type | protein-coding |
Description | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
Other Description | ATPase, H+ transporting, 116kD|OC-116 kDa|T-cell immune response cDNA 7|T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a|V-ATPase 116-kDa|V-type proton ATPase 116 kDa subunit a|V-type proton ATPase 116 kDa subunit a isoform 3|osteoclastic proton pump 116 kDa subunit|specific 116-kDa vacuolar proton pump subunit|vacuolar proton translocating ATPase 116 kDa subunit A |
Swissprots | O75877 Q8WVC5 Q13488 |
Accessions | AAD31081 EAW74689 EAW74690 EAW74691 EAW74692 Q13488 AA625923 AF025374 AAC35742 AF497545 AAM18704 AW083897 AY548967 AAS59834 AY548968 AAS59835 AY548969 AAS59836 AY548970 AAS59837 AY548971 AAS59838 AY548972 AY708388 AAU20795 AY708389 AY708390 AY708391 BC018133 AAH18133 BC032465 AAH32465 BX388184 EU176593 ABW03394 HG503906 U45285 AAA97878 XM_005273709 XP_005273766 XM_011544726 XP_011543028 XM_011544727 XP_011543029 XM_011544728 XP_011543030 XM_011544729 XP_011543031 XR_949754 NM_006019 NP_006010 NM_006053 NP_006044 |
Function | Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Isoform long is highly expressed in osteoclastomas. Isoform short is highly expressed in thymus. |
Top Pathways | Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome |
Human TCIRG1 full length protein - ab160939 from Abcam
|
||||||||||
Human TCIRG1 protein fragment - ab160940 from Abcam
|
||||||||||
Human TCIRG1 protein fragment - ab160941 from Abcam
|
||||||||||
TIRC7 / TCIRG1 Antibody Blocking Peptide - LS-E31311 from LifeSpan Bioscience
|
||||||||||
Recombinant Human TCIRG1 Protein - H00010312-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human TCIRG1 Protein - H00010312-Q02 from Novus Biologicals
|
||||||||||
TCIRG1 Recombinant Protein - H00010312-P01 from Novus Biologicals
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-P01-10 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-P01-25 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-Q01-10 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-Q01-25 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-Q02 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-Q02-10 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C - H00010312-Q02-25 from Acris Antibodies
|
||||||||||
TCIRG1 / ATP6N1C (N-term) Control Peptide - AP55500CP-N from Acris Antibodies
|
||||||||||
TCIRG1 Peptide - 6973P from ProSci
|
||||||||||
TCIRG1 fusion protein - ag3378 from Proteintech Group
|
||||||||||
Recombinant T-Cell, Immune Regulator 1 (TCIRG1) - RPM347Hu01 from Uscn Life Science Inc.
|
||||||||||
TCIRG1 Protein - NBP1-89333PEP from Novus Biologicals
|
||||||||||
TCIRG1 Peptide, Human - M34GP15734H from Creative Peptides
|