TCIRG1

Gene Symbol	TCIRG1
Entrez Gene	10312
Alt Symbol	ATP6N1C, ATP6V0A3, Atp6i, OC-116kDa, OC116, OPTB1, Stv1, TIRC7, Vph1, a3
Species	Human
Gene Type	protein-coding
Description	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Other Description	ATPase, H+ transporting, 116kD\|OC-116 kDa\|T-cell immune response cDNA 7\|T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a\|V-ATPase 116-kDa\|V-type proton ATPase 116 kDa subunit a\|V-type proton ATPase 116 kDa subunit a isoform 3\|osteoclastic proton pump 116 kDa subunit\|specific 116-kDa vacuolar proton pump subunit\|vacuolar proton translocating ATPase 116 kDa subunit A
Swissprots	O75877 Q8WVC5 Q13488
Accessions	AAD31081 EAW74689 EAW74690 EAW74691 EAW74692 Q13488 AA625923 AF025374 AAC35742 AF497545 AAM18704 AW083897 AY548967 AAS59834 AY548968 AAS59835 AY548969 AAS59836 AY548970 AAS59837 AY548971 AAS59838 AY548972 AY708388 AAU20795 AY708389 AY708390 AY708391 BC018133 AAH18133 BC032465 AAH32465 BX388184 EU176593 ABW03394 HG503906 U45285 AAA97878 XM_005273709 XP_005273766 XM_011544726 XP_011543028 XM_011544727 XP_011543029 XM_011544728 XP_011543030 XM_011544729 XP_011543031 XR_949754 NM_006019 NP_006010 NM_006053 NP_006044
Function	Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation. {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity	Isoform long is highly expressed in osteoclastomas. Isoform short is highly expressed in thymus.
Top Pathways	Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome

TCIRG1 (H-70) - sc-368112 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

TCIRG1 (N-13) - sc-162300 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TCIRG1 (N-13): sc-162300. Western blot analysis of TCIRG1 expression in HeLa whole cell lysate.

Anti-TCIRG1 antibody - ab139812 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TCIRG1 antibody (ab139812) at 0.5 µg/mlLane 1 : EL4 cell lysateLane 2 : EL4 cell lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-TCIRG1 antibody - ab56607 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab56607 TCIRG1 antibody at 1ug/ml.

Anti-TIRC7 / TCIRG1 Antibody (aa5-22) - LS-C148963 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-TIRC7 / TCIRG1 Antibody (aa5-22) - LS-C143734 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-TIRC7 / TCIRG1 Antibody (N-Terminus) - LS-C153628 from LifeSpan Bioscience

Prices	$325.00, $890.00
Sizes	100 µg, 500 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of TCIRG1 in EL4 cell lysate with TCIRG1 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.

TCIRG1 Antibody - NBP1-89333 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: TCIRG1 Antibody [NBP1-89333] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.

TCIRG1 Antibody - 43480002 from Novus Biologicals

Prices	$369.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

TCIRG1 Antibody (6H3) - H00010312-M01 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6H3

TCIRG1 Antibody (6H3) - H00010312-M01A from Novus Biologicals

Prices	$349.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	6H3

TCIRG1 Antibody (7H20) - H00010312-M02A from Novus Biologicals

Prices	$349.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	7H20

TCIRG1 Antibody - H00010312-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Anti-TCIRG1 antibody produced in rabbit - HPA038742 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-TCIRG1: <B>Cat. No. HPA038742</B>: Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.

Monoclonal Anti-TCIRG1 antibody produced in mouse - SAB1404814 from Sigma-Aldrich

Prices	$347.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	6H3

<B>Immunoblotting</B><BR/>Monoclonal Anti-TCIRG1: <B>Cat. No. SAB1404814</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.1 kDa using immunogen protein lysate.

Anti-TCIRG1 antibody produced in mouse - SAB1401519 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Polyclonal Anti-TCIRG1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401519</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~68.80 kDa using TCIRG1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

TCIRG1 antibody - orb75824 from Biorbyt

Prices	$723.00
Sizes	100 μg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of EL4 cell lysate at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide using TCIRG1 antibody

Rabbit anti-human T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 (OACA02361) - OACA02361 from Aviva Systems Biology

Prices	$425.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

TCIRG1 antibody - 70R-20741 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Tcirg1 Antibody - abx116013 from Abbexa

Host	Rabbit
Clonality	Polyclonal

TCIRG1 / ATP6N1C antibody - 12649-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Immunofluorescent analysis of HepG2 cells, using TCIRG1 antibody 12649-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

TCIRG1 / ATP6N1C (N-term) antibody - AP55500PU-N from Acris Antibodies

Prices	$340.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of TCIRG1 in EL4 cell lysate with TCIRG1 antibody cat.-No AP55500PU-N at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.

TCIRG1 / ATP6N1C antibody - H00010312-A01 from Acris Antibodies

Prices	$300.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

TCIRG1 / ATP6N1C antibody - H00010312-B01P from Acris Antibodies

Prices	$360.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot analysis of TCIRG1 expression in transfected 293T cell line (H00010312-T02) by TCIRG1 MaxPab polyclonal antibody. Lane 1: TCIRG1 transfected lysate(68.80 KDa). Lane 2: Non-transfected lysate.

TCIRG1 / ATP6N1C antibody - H00010312-M01 from Acris Antibodies

Prices	$360.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6H3

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