PLA2G16

Gene Symbol PLA2G16
Entrez Gene 11145
Alt Symbol AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3
Species Human
Gene Type protein-coding
Description phospholipase A2, group XVI
Other Description Ca-independent phospholipase A1/2|H-rev 107 protein homolog|HRAS-like suppressor 1|HRAS-like suppressor 3|adipose-specific PLA2|adipose-specific phospholipase A2|group XVI phospholipase A1/A2|group XVI phospholipase A2|renal carcinoma antigen NY-REN-65
Swissprots Q3SYI3 B7XAK5 B2R7Q4 P53816 Q9HDD1
Accessions EAW74158 EAW74159 EAW74160 P53816 AB030814 BAB08108 AB439591 BAH08749 AF317086 AAL26892 AI374456 AI590735 AK313075 BAG35901 AU099540 AX775893 CAE11646 BC001387 AAH01387 BC103807 AAI03808 BC103808 AAI03809 BG719903 CK003948 DQ892568 ABM83494 DQ895783 ABM86709 X92814 CAA63423 XM_006718426 XP_006718489 XM_011544741 XP_011543043 NM_001128203 NP_001121675 NM_007069 NP_009000
Function Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O- acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity. {ECO:0000250, ECO:0000269|PubMed:17374643, ECO:0000269|PubMed:19615464}.
Subcellular Location Cytoplasm. Cytoplasm, perinuclear region {ECO:0000250}. Membrane; Single-pass membrane protein.
Tissue Specificity Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down- regulated in some ovarian carcinomas and testicular germ cell tumors. {ECO:0000269|PubMed:11526504, ECO:0000269|PubMed:11973642, ECO:0000269|PubMed:19615464, ECO:0000269|PubMed:9771974}.
Top Pathways Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism, alpha-Linolenic acid metabolism, Glycerophospholipid metabolism

HRASLS3 (G-12) - sc-168105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HRASLS3 antibody - ab168489 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HRASLS3 antibody (ab168489) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with HRASLS3Lane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-HRASLS3 antibody - ab88447 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-HRASLS3 antibody (ab88447) at 1 µg/ml + Human placenta tissue lysate at 50 µgSecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-HRASLS3 antibody - ab104454 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab104454, at 5 µg/ml, staining HRASLS3 in formalin-fixed, paraffin-embedded Human Brain Cortex by Immunohistochemistry, followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-HRASLS3 antibody - ab56774 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56774 HRASLS3 antibody at 1ug/ml.

Anti-HRASLS3 antibody [1A5] - ab180392 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A5
All lanes : Anti-HRASLS3 antibody [1A5] (ab180392) at 1/4000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY HRASLS3 cDNALysates/proteins at 5 µg per lane.

Anti-HRASLS3 antibody - C-terminal - ab175532 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HRASLS3 antibody - C-terminal (ab175532) at 1/1000 dilution + Mouse kidney tissue lysate at 15 µgdeveloped using the ECL technique

Anti-PLA2G16 / HRASLS3 Antibody (clone 1B10-2D9) - LS-C139202 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B10-2D9

Anti-PLA2G16 / HRASLS3 Antibody - LS-C131411 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-PLA2G16 / HRASLS3 Antibody - LS-C310660 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G16 / HRASLS3 Antibody - LS-C308298 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PLA2G16 / HRASLS3 Antibody (aa104-132) - LS-C165010 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HRASLS3 Antibody western blot of mouse kidney tissue lysates (15 ug/lane). The HRASLS3 antibody detected HRASLS3 protein (arrow).

Anti-PLA2G16 / HRASLS3 Antibody (clone 1B6) - LS-C338261 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLA2G16 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1H1) - LS-C338260 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLA2G16 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1G1) - LS-C338299 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLA2G16 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1F5) - LS-C338264 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLA2G16 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (clone 4C4-2A11) - LS-C139294 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C4-2A11
Western blot of PLA2G16 expression in transfected 293T cell line by PLA2G16 monoclonal antibody (M02), clone 4C4-2A11.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1B12) - LS-C338265 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLA2G16 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1E9) - LS-C338297 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLA2G16 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1C9) - LS-C338263 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C9
Anti-PLA2G16 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PLA2G16.

Anti-PLA2G16 / HRASLS3 Antibody (aa2-15) IHC-plus™ - LS-B3287 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PLA2G16 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3287 concentration 5 ug/ml.

Anti-PLA2G16 / HRASLS3 Antibody (clone 1A5) - LS-C338259 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A5
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-PLA2G16 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

PLA2G16/HRASLS3 Antibody - AF6190 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of human heart tissue. PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human PLA2G16 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6190) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for PLA2G16 at approximately XXX kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group XXX.

PLA2G16/HRASLS3 Antibody - H00011145-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PLA2G16/HRASLS3 Antibody [H00011145-B01P] - Analysis of HRASLS3 expression in human placenta.

PLA2G16/HRASLS3 Antibody - H00011145-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PLA2G16/HRASLS3 Antibody [H00011145-D01P] - Analysis of PLA2G16 expression in human spleen.
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