PLA2G16

Gene Symbol PLA2G16
Entrez Gene 11145
Alt Symbol AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3
Species Human
Gene Type protein-coding
Description phospholipase A2, group XVI
Other Description Ca-independent phospholipase A1/2|H-rev 107 protein homolog|HRAS-like suppressor 1|HRAS-like suppressor 3|adipose-specific PLA2|adipose-specific phospholipase A2|group XVI phospholipase A1/A2|group XVI phospholipase A2|renal carcinoma antigen NY-REN-65
Swissprots Q3SYI3 B7XAK5 B2R7Q4 P53816 Q9HDD1
Accessions EAW74158 EAW74159 EAW74160 P53816 AB030814 BAB08108 AB439591 BAH08749 AF317086 AAL26892 AI374456 AI590735 AK313075 BAG35901 AU099540 AX775893 CAE11646 BC001387 AAH01387 BC103807 AAI03808 BC103808 AAI03809 BG719903 CK003948 DQ892568 ABM83494 DQ895783 ABM86709 X92814 CAA63423 XM_006718426 XP_006718489 XM_011544741 XP_011543043 NM_001128203 NP_001121675 NM_007069 NP_009000
Function Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O- acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity. {ECO:0000250, ECO:0000269|PubMed:17374643, ECO:0000269|PubMed:19615464}.
Subcellular Location Cytoplasm. Cytoplasm, perinuclear region {ECO:0000250}. Membrane; Single-pass membrane protein.
Tissue Specificity Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down- regulated in some ovarian carcinomas and testicular germ cell tumors. {ECO:0000269|PubMed:11526504, ECO:0000269|PubMed:11973642, ECO:0000269|PubMed:19615464, ECO:0000269|PubMed:9771974}.
Top Pathways Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism, alpha-Linolenic acid metabolism, Glycerophospholipid metabolism

HRASLS3 CRISPR/Cas9 KO Plasmid (h) - sc-409231 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 HDR Plasmid (h) - sc-409231-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 Double Nickase Plasmid (h) - sc-409231-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 Double Nickase Plasmid (h2) - sc-409231-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 CRISPR Activation Plasmid (h) - sc-409231-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 CRISPR Activation Plasmid (h2) - sc-409231-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 Lentiviral Activation Particles (h) - sc-409231-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 Lentiviral Activation Particles (h2) - sc-409231-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HRASLS3 siRNA (h) - sc-96963 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HRASLS3 shRNA Plasmid (h) - sc-96963-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HRASLS3 shRNA (h) Lentiviral Particles - sc-96963-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLA2G16/HRASLS3 RNAi - H00011145-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU014621 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16886 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16886 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLA2G16 siRNA (Human) - CRH7627 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLA2G16 (NM_007069.3) - SHH376712 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLA2G16 siRNA - orb268129 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLA2G16 shRNA Plasmid (Human) - CHH7627 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLA2G16 miRNA 3'UTR clone - MiUTR3H-13054 from Creative biogene

Species Reactivities Human

PLA2G16 miRNA 3'UTR clone - MiUTR3H-13055 from Creative biogene

Species Reactivities Human
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