DAGLA

Gene Symbol DAGLA
Entrez Gene 747
Alt Symbol C11orf11, DAGL(ALPHA), DAGLALPHA, NSDDR
Species Human
Gene Type protein-coding
Description diacylglycerol lipase, alpha
Other Description DGL-alpha|neural stem cell-derived dendrite regulator|sn1-specific diacylglycerol lipase alpha
Swissprots Q6WQJ0 Q9Y4D2 A7E233
Accessions EAW73959 EAW73960 EAW73961 EAW73962 Q9Y4D2 AB014559 BAA31634 AI702626 AY275377 AAQ17119 BC150176 AAI50177 BC150195 AAI50196 BC152453 AAI52454 BI963857 XM_005274230 XP_005274287 XM_011545235 XP_011543537 XM_011545236 XP_011543538 NM_006133 NP_006124
Function Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses. {ECO:0000269|PubMed:14610053}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in brain and pancreas. {ECO:0000269|PubMed:14610053, ECO:0000269|PubMed:16051747}.
Top Pathways Retrograde endocannabinoid signaling

Panoply™ Human DAGLA Knockdown Stable Cell Line - CSC-DC004015 from Creative biogene

Category Cell Line
Species Human
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