UBE2A

Gene Symbol	UBE2A
Entrez Gene	7319
Alt Symbol	HHR6A, MRXS30, MRXSN, RAD6A, UBC2
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2A
Other Description	RAD6 homolog A|ubiquitin carrier protein A|ubiquitin-conjugating enzyme E2 A|ubiquitin-protein ligase A
Swissprots	Q96FX4 A6NMF5 P49459 B2R7R9 D3DWI1 A6NGR2 Q4TTG1 A6NFE9
Accessions	AAL58874 AAY46159 CBX53867 CBX53868 CBX53869 EAW89861 EAW89862 EAW89863 P49459 AI784380 AK223045 BAD96765 AK223064 BAD96784 AK297696 BAG60054 AK301675 BAG63148 AK313092 BAG35916 AL701289 BC010175 AAH10175 BC042021 BI093289 D28459 BAA05825 DA068506 DA599154 DQ893386 ABM84312 DQ896706 ABM87705 M74524 AAA35981 NM_001282161 NP_001269090 NM_003336 NP_003327 NM_181762 NP_861427 NM_181777
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. {ECO:0000269|PubMed:16337599, ECO:0000269|PubMed:20061386}.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Rad6 full length protein - ab151928 from Abcam Category Protein Source E. coli Species Human

Human Rad6 full length protein - ab95493 from Abcam Category Protein Source E. coli Species Human

Human Rad6 full length protein - ab117186 from Abcam Category Protein Source E. coli Species Human

Human Rad6 peptide - ab28495 from Abcam Category Peptide

Rad6 protein (His tag) - ab127412 from Abcam Category Protein Source E. coli Species Human

HR6A/UBE2A Recombinant Protein - H00007319-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HR6A/UBE2A Protein - NBP1-44378 from Novus Biologicals Category Protein Prices $279.00 Sizes 100 µg Species Human

UBE2A Protein - GTX100426-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Recombinant Human His6-HR6A/UBE2A, CF - E2-612-050 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

Recombinant Human His6-HR6A/UBE2A, CF - E2-612-100 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal 6-His tag

UBE2A Protein (OPPA02388) - OPPA02388 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human HR6A protein - orb49713 from Biorbyt Category Protein Prices $179.00, $264.00, $825.00, $1,148.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human UBC2 protein - orb107812 from Biorbyt Category Protein Prices $221.00, $357.00, $425.00, $629.00 Sizes 10 μg, 50 μg, 100 μg, 250 μg Source E.coli Species Human

Human UBE2A protein - orb90292 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E.coli Species Human

Human UBE2A protein (His Tag) - orb139837 from Biorbyt Category Protein Prices $196.00, $298.00 Sizes 50 μg, 100 μg Source E. coli Species Human

UBE2A protein (His tag) - 80R-1319 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

UBE2A/B Blocking Peptide - abx063397 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Zebrafish

UBE2A / RAD6A (1-152, His-tag) - AR09465PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

UBE2A / RAD6A (1-152, His-tag) - AR09465PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

UBE2A / RAD6A - H00007319-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

UBE2A / RAD6A - H00007319-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

UBE2A, 1-152aa, Human, His tag, E.coli - 01-2399-A from ARP American Research Products Category Protein Prices $159.00, $339.00, $749.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Ubiquitin-Conjugating Enzyme E2 A, UBE2A, Human, Recombinant - 19-C183 from ARP American Research Products Category Protein Prices $109.00 Sizes 10 µg Source E. coli Species Human

UBE2A fusion protein - ag1567 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

UBE2A Human - ENPS-521 from NeoScientific Category Protein Prices $65.00, $169.00, $2,925.00 Sizes 5 µg, 25 µg, 1 mg Source Escherichia Coli. Species Human

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