PAX5

Gene Symbol PAX5
Entrez Gene 5079
Alt Symbol ALL3, BSAP
Species Human
Gene Type protein-coding
Description paired box 5
Other Description B-cell lineage specific activator|paired box homeotic gene 5|paired box protein Pax-5|paired domain gene 5|transcription factor PAX 5
Swissprots Q6S729 C0KTF7 A3QVP7 O75933 C0KTF9 Q6S730 Q6S732 C0KTG0 A3QVP6 Q5SFM2 C0KTF8 Q6S731 Q02548 A3QVP8 C0KTF6 Q6S728
Accessions AAB16832 AAB16833 AAC69188 AAK25737 AAK70869 AAK70870 ABK41900 EAW58294 EAW58295 EAW58296 EAW58297 EAW58298 EAW58299 Q02548 AF080573 AAC35286 AY463952 AAR27590 AY463953 AAR27591 AY463954 AAR27592 AY463955 AAR27593 AY463956 AAR27594 AY463957 AAR27595 BC156189 AAI56190 BC156927 AAI56928 FJ626406 ACM91589 FJ626407 ACM91590 FJ626408 ACM91591 FJ626409 ACM91592 FJ626410 ACM91593 FJ626411 ACM91594 FJ626412 ACM91595 FJ626413 ACM91596 FJ626414 ACM91597 FJ626415 ACM91598 FJ626416 ACM91599 FJ626417 ACM91600 FJ626418 ACM91601 FJ626419 ACM91602 FJ626420 ACM91603 FJ626421 ACM91604 FJ626422 ACM91605 FJ626423 ACM91606 FJ626424 ACM91607 FJ626425 ACM91608 M96944 AAA58397 U62539 AAB09533 XM_005251481 XP_005251538 XM_011517896 XP_011516198 XM_011517897 XP_011516199 NM_001280547 NP_001267476 NM_001280548 NP_001267477 NM_001280549 NP_001267478 NM_001280550 NP_001267479 NM_001280551 NP_001267480 NM_001280552 NP_001267481 NM_001280553 NP_001267482 NM_001280554 NP_001267483 NM_001280555 NP_001267484 NM_001280556 NP_001267485 NM_016734 NP_057953 NR_103999 NR_104000
Function May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Subcellular Location Nucleus.
Top Pathways Transcriptional misregulation in cancer

PAX5 (D19F8) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate) - 11849 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D19F8
Flow cytometric analysis of Jurkat (blue) and Ramos (green) cells using PAX5 (D19F8) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate).

PAX5 (D19F8) XP ® Rabbit mAb (Alexa Fluor ® 647 Conjugate) - 11852 from Cell Signaling Technology

Host Rabbit
Clonality Monoclonal
Clone D19F8
Flow cytometric analysis of Jurkat (blue) and Ramos (green) cells using PAX5 (D19F8) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate).

PAX5 (D19F8) XP ® Rabbit mAb (Alexa Fluor ® 555 Conjugate) - 11855 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D19F8
Confocal immunofluorescent analysis of Ramos (left) and MCF7 (right) cells using PAX5 (D19F8) XP ® Rabbit mAb (Alexa Fluor ® 555 Conjugate) (red). Actin filaments were labeled with Alexa Fluor ® 488 phalloidin (green).

PAX5 (D7H5X) XP ® Rabbit mAb - 12709 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7H5X
Western blot analysis of extracts from various cell lines using PAX5 (D7H5X) XP ® Rabbit mAb (upper) and β-actin (D6A8) Rabbit mAb #8457 (lower).

PAX5 (D19F8) XP ® Rabbit mAb - 8970 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D19F8
Western blot analysis of extracts from various cell lines using PAX5 (D19F8) XP ® Rabbit mAb.

Pax-5 (C-20) - sc-1974 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pax-5 (C-20): sc-1974. Western blot analysis of Pax-5 expression in WEHI-231 (A) and U-937 (B) whole cell lysates.

Pax-5 (E-9) - sc-55515 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pax-5 (E-9): sc-55515. Western blot analysis of Pax-5 expression in NAMALWA whole cell lysate.

Pax-5 (N-19) - sc-1975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pax-5 (N-19): sc-1975. Immunofluorescence staining of methanol-fixed NAMALWA cells showing nuclear staining.

Pax-5 (1H9) - sc-130922 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Pax-5 (1H9): sc-130922. Western blot analysis of Pax-5 expression in non-transfected 293: sc-110760 (A), human Pax-5 transfected 293: sc-176172 (B) and NAMALWA (C) whole cell lysates and BJAB nuclear extract (D).

Pax-5 (A-11) - sc-13146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pax-5 (A-11): sc-13146. Western blot analysis of Pax-5 expression in NAMALWA whole cell lysate.

Anti-PAX5 antibody - ab183575 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PAX5 antibody (ab183575) at 1/1000 dilutionLane 1 : Ramos whole cell lysateLane 2 : Daudi whole cell lysateLane 3 : Raji whole cell lysateLane 4 : Jurkat whole cell lysateLane 5 : A20 whole cell lysateLysates/proteins at 75 µg per lane.SecondaryGoat anti rabbit HRP at 1/500 dilution

Anti-PAX5 antibody - ab15164 from Abcam

Prices $390.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
PAX5 was immunoprecipitated using 0.5mg Ramos whole cell extract, 5µg of Rabbit polyclonal to PAX5 and 50µl of protein G magnetic beads (+). No antibody was added to the control (-).The antibody was incubated under agitation with Protein G beads for 10min, Ramos whole cell extract lysate diluted in RIPA buffer was added to each sample and incubated for a further 10min under agitation.Proteins were eluted by addition of 40µl SDS loading buffer and incubated for 10min at 70°C; 10µl of each sample was separated on a SDS PAGE gel, transferred to a nitrocellulose membrane, blocked with 5% BSA and probed with ab15164.Secondary: Mouse monoclonal [SB62a] Secondary Antibody to Rabbit IgG light chain (HRP) (ab99697).Band: 42kDa; PAX5

Anti-PAX5 antibody - ab122885 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-PAX5 antibody - ab140341 from Abcam

Prices $376.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelling Pax5 using ab140341 at 1/50 dilution

Anti-PAX5 antibody - ab55492 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
PAX5 antibody (ab55492) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-PAX5 antibody - ab53046 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PAX5 antibody (ab53046) at 1/500 dilutionLane 1 : 293 cell extractLane 2 : 293 cell extract with immunising peptide

Anti-PAX5 antibody - ab2935 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PAX5 antibody [1EW] - ab67005 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1EW
Human acute lymphoblastic leukemia: immunohistochemical staining for Pax5 with 1/20 ab67005. Note nuclear staining of B cells. Paraffin section.

Anti-Pax5 antibody [7D3] - ab191371 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 7D3
Anti-Pax5 antibody [7D3] (ab191371) at 1/500 dilution + Human Pax5 recombinant protein

Anti-PAX5 antibody [8F9] - ab117705 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 8F9
Anti-PAX5 antibody [8F9] (ab117705) + IMR-32 cell lysate

Anti-PAX5 antibody [BV6] - ab56176 from Abcam

Prices $376.00
Sizes 250 µl
Host Rabbit
Clonality Monoclonal
Clone BV6
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue, staining PAX5 with ab56176. Staining was detected using DAB.

Anti-PAX5 antibody [BV6], prediluted - ab56179 from Abcam

Prices $370.00
Sizes 6 ml
Host Rabbit
Clonality Monoclonal
Clone BV6

Anti-PAX5 antibody [EPR3729] - ab92512 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3729
All lanes : Anti-PAX5 antibody [EPR3729] (ab92512) at 1/1000 dilutionLane 1 : Ramos cell lysateLane 2 : Daudi cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PAX5 antibody [EPR3730(2)] - ab109443 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3730(2)
All lanes : Anti-PAX5 antibody [EPR3730(2)] (ab109443) at 1/10000 dilutionLane 1 : Ramos lysateLane 2 : Human tonsil lysateLane 3 : Daudi lysates Lysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PAX5 antibody [mAbcam52588] - ab52588 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone mAbcam52588
All lanes : Anti-PAX5 antibody [mAbcam52588] (ab52588) at 1 µg/mlLane 1 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate (blocked with 1% milk)Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate (blocked with 1% Milk)Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.
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