CERS1

Gene Symbol	CERS1
Entrez Gene	10715
Alt Symbol	EPM8, LAG1, LASS1, UOG1
Species	Human
Gene Type	protein-coding
Description	ceramide synthase 1
Other Description	longevity assurance (LAG1, S. cerevisiae) homolog 1|longevity assurance gene 1 protein homolog 1|protein UOG-1|upstream of GDF1
Swissprots	P27544
Accessions	AAD16892 EAW84745 EAW84746 P27544 AI671814 AK293463 BAG56958 AL120193 BC032615 BC084582 AAH84582 BF343384 BM925585 BX453803 NM_001290265 NP_001277194 NM_021267 NP_067090 NM_198207 NP_937850
Function	May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LASS1 CRISPR/Cas9 KO Plasmid (h) - sc-405614 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 HDR Plasmid (h) - sc-405614-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 Double Nickase Plasmid (h) - sc-405614-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 Double Nickase Plasmid (h2) - sc-405614-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 CRISPR Activation Plasmid (h) - sc-405614-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 CRISPR Activation Plasmid (h2) - sc-405614-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 Lentiviral Activation Particles (h) - sc-405614-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 Lentiviral Activation Particles (h2) - sc-405614-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LASS1 siRNA (h) - sc-62543 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LASS1 shRNA Plasmid (h) - sc-62543-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LASS1 shRNA (h) Lentiviral Particles - sc-62543-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LASS1 RNAi - H00010715-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

LASS1 RNAi - H00010715-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU016651 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11560 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11560 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12468 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr12468

CERS1 siRNA (Human) - CRH7299 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CERS1 - MBS8202815 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human Cers1 (NM_021267.3) - SHH262113 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human LASS1(NM_021267.3) - SHH142805 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human LASS1(NM_198207.2) - SHH142823 from Creative biogene Category siRNA Species Reactivities Human

Human CERS1 siRNA - orb267801 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CERS1 shRNA Plasmid (Human) - CHH7299 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CERS1 miRNA 3'UTR clone - MiUTR1H-05580 from Creative biogene Species Reactivities Human

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