ADA

Gene Symbol	ADA
Entrez Gene	100
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	adenosine deaminase
Other Description	adenosine aminohydrolase
Swissprots	Q6LA59 P00813 Q53F92
Accessions	AAA78791 CAA26130 CBX85542 CBX85614 EAW75904 EAW75905 EAW75906 EAW75907 P00813 AK123988 AK223397 BAD97117 AL832305 BC007678 AAH07678 BC040226 AAH40226 BI601734 DQ892681 ABM83607 DQ895924 ABM86850 KJ534760 AHW56400 S66773 AAB28742 X02994 CAA26734 XM_005260236 XP_005260293 XM_011528478 XP_011526780 XM_011528479 XP_011526781 XR_244129 NM_000022 NP_000013
Function	Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion. {ECO:0000269|PubMed:11772392}.
Subcellular Location	Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion.
Tissue Specificity	Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues.
Top Pathways	Primary immunodeficiency, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ADA-Over-expression-Lysate - LY12250a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ADA 293T Cell Transient Overexpression Lysate(Denatured) - H00000100-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

Adenosine deaminase Lysate (Non-Denatured) - L024T6 from Acris Antibodies Category Cell Lysate Prices $290.00 Sizes 100 µg

ADA overexpression lysate - LY424974 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

Adenosine Deaminase/ADA Overexpression Lysate (Denatured) - H00000100-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Adenosine Deaminase/ADA Overexpression Lysate (Native) - L024T6 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µg Species Human

adenosine deaminase (h): 293 Lysate - sc-114383 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

adenosine deaminase (h): 293T Lysate - sc-159789 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

adenosine deaminase (h2): 293T Lysate - sc-170433 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

adenosine deaminase (h3): 293T Lysate - sc-158238 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Human ADA / Adenosine deaminase Insect Cell Lysate (WB positive control) - 14737-H08BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human ADA Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175333 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human ADA Knockdown Stable Cell Line - CSC-DC000224 from Creative biogene Category Cell Line Species Human

Human ADA Knockout Cell Line-HeLa - CSC-RT1387 from Creative biogene Category Cell Line Species Human

ADA KO Cell Lysate-HeLa - CLKO-1239 from Creative biogene Category Cell Lysate

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